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Butirosin A

National Institutes of Health

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Butirosin Sulfate

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1982
1982
Deoxy derivatives of butirosin A and 5"-amino-5"-deoxybutirosin A, aminoglycoside antibiotics resistant to bacterial 3'-phosphorylative enzymatic inactivation. Synthesis and NMR studies.
3'-Deoxybutirosin A (4), 5"-amino-3', 5"-dideoxybutirosin A (6), and 5"-amino-4', 5"-dideoxybutirosin A (7) were prepared by… 
1978
1978
Mutational biosynthesis of butirosin analogs. III. 6'-N-methylbutirosins and 3', 4'-dideoxy-6'-c-methylbutirosins, new semisynthetic aminoglycosides.
Two pairs of butirosin analogs were isolated from the fermentation broths obtained by cultivating a neamine-negative mutant of… 
1978
1978
Mutational biosynthesis of butirosin analogs. II. 3', 4'-Dideoxy-6'-N-methylbutirosins, new semisynthetic aminoglycosides.
A pair of new butirosin analogs was isolated from the fermentation broth obtained by cultivating a neamine-negative mutant of the… 
1978
1978
An approach to the biosynthetic pathway of butirosins and the related antibiotics.
Sir: In the foregoing communications', we have reported the preparation of new butirosin analogs using two neamine-negative… 
Highly Cited
1972
Highly Cited
1972
A new enzyme in Escherichia coli carrying R-factor phosphorylating 3'-hydroxyl of butirosin A, kanamycin, neamine and ribostamycin.