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Benserazide

Known as: DL-Seryltrihydroxybenzylhydrazine, DL-Serine 2-((2,3,4-trihydroxyphenyl)methyl)hydrazide, Benserazide [Chemical/Ingredient] 
An inhibitor of DOPA DECARBOXYLASE that does not enter the central nervous system. It is often given with LEVODOPA in the treatment of parkinsonism… 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (3)

Antiparkinson AgentsDopaminergic AgentsEnzyme Inhibitors

Narrower (4)

Benserazide / LevodopaBenserazide hydrochlorideMadoparRo 4-4602
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Brain and peripheral pharmacokinetics of levodopa in the cynomolgus monkey following administration of opicapone, a third generation nitrocatechol COMT inhibitor
2013
2013
Dopamine receptor activation increases glial cell line-derived neurotrophic factor in experimental stroke
Review
2011
Review
2011
Parkinson's syndrome and Parkinson's disease in mitochondrial disorders
In the majority of cases, mitochondrial disorders are multisystem conditions that most frequently affect the skeletal muscle… 
2008
2008
Intrastriatal inhibition of aromatic amino acid decarboxylase prevents l-DOPA-induced dyskinesia: A bilateral reverse in vivo microdialysis study in 6-hydroxydopamine lesioned rats
Highly Cited
2007
Highly Cited
2007
Changes on 5-HT2 receptor mRNAs in striatum and subthalamic nucleus in Parkinson's disease model
Highly Cited
2003
Highly Cited
2003
Binding site of salsolinol: its properties in different regions of the brain and the pituitary gland of the rat
2003
2003
Effects of peripheral and central catechol-O-methyltransferase inhibition on striatal extracellular levels of dopamine: a microdialysis study in freely moving rats.
Highly Cited
1999
Highly Cited
1999
Dual effects of l-3,4-dihydroxyphenylalanine on aromatic l-amino acid decarboxylase, dopamine release and motor stimulation in the reserpine-treated rat: evidence that behaviour is dopamine…
Highly Cited
1995
Highly Cited
1995
Non-amphetaminic mechanism of stimulant locomotor effect of modafinil in mice
1978
1978
The L‐dopa on‐off effect in parkinson disease: Treatment by transient drug withdrawal and dopamine receptor resensitization
It has been suggested that patients with Parkinson disease partially compensate for neuron loss by developing denervation… 
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