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Basic Helix-Loop-Helix Transcription Factors

Known as: bHLH Transcription Factors, Basic HLH Protein, BHLH Protein 
bHLH class proteins are sequence-specific DNA-binding proteins that contain a conserved 50-amino acid HLH domain consisting of two alpha-helices… 
National Institutes of Health

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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2000
2000
A novel type of calmodulin interaction in the inhibition of basic helix-loop-helix transcription factors.
Calmodulin is the predominant intracellular receptor for Ca(2+) signals, mediating the regulation of numerous cellular processes… 
2000
2000
Cell type-dependent transactivation or repression of mesoderm-restricted basic helix-loop-helix protein, POD-1/Capsulin
A family of basic-helix-loop-helix (bHLH) nuclear factors play important roles in controlling cell growth and differentiation as… 
1999
1999
A transcription factor involved in skeletal muscle gene expression is deleted in patients with Williams syndrome
Williams-Beuren syndrome (WS) is a developmental disorder caused by a hemizygous microdeletion of approximately 1.4 MB at… 
Review
1998
Review
1998
Calcium regulation of basic helix-loop-helix transcription factors.
Highly Cited
1998
Highly Cited
1998
Regulation of the Drosophila bHLH-PAS protein Sima by hypoxia: functional evidence for homology with mammalian HIF-1 alpha.
Hypoxia inducible factor-1 (HIF-1) is a heterodimeric complex of two basic-helix-loop-helix proteins of the PAS family which is… 
1998
1998
Identification of a Highly Conserved Module in E Proteins Required for in Vivo Helix-loop-helix Dimerization*
Basic helix-loop-helix (bHLH) transcription factors often function as heterodimeric complexes consisting of a tissue-specific… 
1997
1997
Purification and characterization of the Streptomyces lividans initiator protein DnaA
The Streptomyces lividans DnaA protein (73 kDa) consists, like the Escherichia coli DnaA protein (52 kDa), of four domains. The… 
1996
1996
The TAL1/Scl basic helix-loop-helix protein blocks myogenic differentiation and E-box dependent transactivation.
The TAL1 gene is transcriptionally activated by chromosomal translocation in the most common genetic lesion associated with T… 
1993
1993
DNA binding by N- and L-Myc proteins.
N- and L-Myc, like c-Myc, contain adjacent basic region (BR), helix-loop-helix (HLH) and leucine zipper (LZ) motifs, which… 
Review
1992
Review
1992
Activation of muscle-specific transcription by myogenic helix-loop-helix proteins.
Myogenin is a muscle-specific transcription factor that acts as a molecular switch to induce myogenesis. Myogenin shares homology… 
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