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ID2 protein, human

Known as: Inhibitor of DNA Binding 2, Dominant Negative Helix-Loop-Helix Protein, DNA-Binding Protein Inhibitor ID-2, Inhibitor of Differentiation 2 
DNA-binding protein inhibitor ID-2 (134 aa, ~15 kDa) is encoded by the human ID2 gene. This protein is involved in the modulation of DNA binding by… 
National Institutes of Health

Related topics

Related topics

14 relations
Basic Helix-Loop-Helix Transcription FactorsCell Cycle ProteinsCell NucleusCell Proliferation Regulatory Process

Broader (1)

Id2 protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
PDGF Engages an E2F-USP1 Signaling Pathway to Support ID2-Mediated Survival of Proneural Glioma Cells.
Glioblastoma is the most aggressive primary brain tumor and responds poorly to currently available therapies. Transcriptomic… 
Review
2010
Review
2010
SWI/SNF complexes, chromatin remodeling and skeletal myogenesis: it's time to exchange!
Highly Cited
2004
Highly Cited
2004
Highly specific interactions between bHLH transcription factors and chromatin during retina development
Basic helix-loop-helix (bHLH) transcription factors such as atonal homolog 5 (ATH5) and neurogenin 2 (NGN2) determine crucial… 
Review
2003
Review
2003
Helix-Loop-Helix Proteins in Mammary Gland Development and Breast Cancer
The basic helix-loop-helix (bHLH) family of transcription factors functions in the coordinated regulation of gene expression… 
2002
2002
Mammary epithelial cells are not able to undergo pregnancy-dependent differentiation in the absence of the helix-loop-helix inhibitor Id2.
Mammary alveolar development during pregnancy is triggered by hormone signals. The prolactin receptor/Jak2/signal transducer and… 
Highly Cited
1997
Highly Cited
1997
Faithful expression of the Myf-5 gene during mouse myogenesis requires distant control regions: a transgene approach using yeast artificial chromosomes.
Myf-5, a member of the family of four muscle-specific basic helix-loop-helix (bHLH) transcription factors is the first to be… 
Highly Cited
1995
Highly Cited
1995
Interactions of myogenic bHLH transcription factors with calcium-binding calmodulin and S100a (alpha alpha) proteins.
MyoD belongs to a family of myogenic basic helix-loop-helix (bHLH) transcription factors that activate muscle-specific genes. The… 
1994
1994
Posttranscriptional regulation of Id1 activity in cardiac muscle. Alternative splicing of novel Id1 transcript permits homodimerization.
1994
1994
The E box is essential for activity of the cardiac actin promoter in skeletal but not in cardiac muscle.
The sequence CANNTG (E box) is frequently found in the promoters of muscle-specific genes and binds members of the basic helix… 
Highly Cited
1993
Highly Cited
1993
E1A-mediated inhibition of myogenesis correlates with a direct physical interaction of E1A12S and basic helix-loop-helix proteins
The observation that adenovirus E1A gene products can inhibit differentiation of skeletal myocytes suggested that E1A may… 
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