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ID2 protein, human

Known as: Inhibitor of DNA Binding 2, Dominant Negative Helix-Loop-Helix Protein, DNA-Binding Protein Inhibitor ID-2, Inhibitor of Differentiation 2 
DNA-binding protein inhibitor ID-2 (134 aa, ~15 kDa) is encoded by the human ID2 gene. This protein is involved in the modulation of DNA binding by… 
National Institutes of Health

Related topics

Related topics

14 relations
Basic Helix-Loop-Helix Transcription FactorsCell Cycle ProteinsCell NucleusCell Proliferation Regulatory Process

Broader (1)

Id2 protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Elevated Id2 Expression Results in Precocious Neural Stem Cell Depletion and Abnormal Brain Development
Id2 is a helix‐loop‐helix transcription factor essential for normal development, and its expression is dysregulated in many human… 
2009
2009
ERK5 MAP Kinase Regulates Neurogenin1 during Cortical Neurogenesis
The commitment of multi-potent cortical progenitors to a neuronal fate depends on the transient induction of the basic-helix-loop… 
2003
2003
ID2 expression is not associated with MYCN amplification or expression in human neuroblastomas.
MYCN is a biologically and clinically important oncogene in human neuroblastoma as genomic amplification reliably predicts for… 
2003
2003
Synergistic activation of the human orphan nuclear receptor SHP gene promoter by basic helix-loop-helix protein E2A and orphan nuclear receptor SF-1.
The orphan nuclear receptor small heterodimer partner (SHP; NR0B2) is an unusual orphan nuclear receptor that lacks a… 
2000
2000
A cysteine residue in the helix-loop-helix domain of Id2 is critical for homodimerization and function.
Id proteins are negative regulators of basic helix-loop-helix (bHLH) transcription factors. In this study, we compared the… 
1998
1998
Thermodynamics of the DNA binding reaction of transcription factor MASH-1.
MASH-1, a member of the basic helix-loop-helix (BHLH) family of transcription factors, promotes the differentiation of committed… 
1998
1998
Arginine (348) is a major determinant of the DNA binding specificity of transcription factor E12.
The basic helix-loop-helix proteins (BHLH) E12 and E47 bind to DNA in a cell-type specific fashion as heterodimers with… 
Highly Cited
1997
Highly Cited
1997
Faithful expression of the Myf-5 gene during mouse myogenesis requires distant control regions: a transgene approach using yeast artificial chromosomes.
Myf-5, a member of the family of four muscle-specific basic helix-loop-helix (bHLH) transcription factors is the first to be… 
Highly Cited
1995
Highly Cited
1995
Interactions of myogenic bHLH transcription factors with calcium-binding calmodulin and S100a (alpha alpha) proteins.
MyoD belongs to a family of myogenic basic helix-loop-helix (bHLH) transcription factors that activate muscle-specific genes. The… 
1994
1994
Posttranscriptional regulation of Id1 activity in cardiac muscle. Alternative splicing of novel Id1 transcript permits homodimerization.
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