ID2 protein, human

Known as: Inhibitor of DNA Binding 2, Dominant Negative Helix-Loop-Helix Protein, DNA-Binding Protein Inhibitor ID-2, Inhibitor of Differentiation 2 
DNA-binding protein inhibitor ID-2 (134 aa, ~15 kDa) is encoded by the human ID2 gene. This protein is involved in the modulation of DNA binding by… (More)
National Institutes of Health

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Highly Cited
2006
Highly Cited
2006
In the developing nervous system, Id2 (inhibitor of DNA binding 2, also known as inhibitor of differentiation 2) enhances cell… (More)
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Highly Cited
2005
Highly Cited
2005
Autosomal-dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease and is characterized by… (More)
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Highly Cited
2004
Highly Cited
2004
Olig1 and Olig2 are closely related basic helix-loop-helix (bHLH) transcription factors that are expressed in myelinating… (More)
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Highly Cited
2003
Highly Cited
2003
The basic/helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that bind as dimers to specific DNA target… (More)
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Highly Cited
2001
Highly Cited
2001
Compared to neurons, the intracellular mechanisms that control glial differentiation are still poorly understood. We show here… (More)
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Highly Cited
2000
Highly Cited
2000
In mammalian cells, Id proteins coordinate proliferation and differentiation. Id2 is a dominant-negative antagonist of basic… (More)
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Highly Cited
1999
Highly Cited
1999
Transcription factors with a basic helix–loop–helix (HLH) motif have been shown to be crucial for various cell differentiation… (More)
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Highly Cited
1997
Highly Cited
1997
We identified a gene of the fungal pathogen Candida albicans, designated EFG1, whose high-level expression stimulates… (More)
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Highly Cited
1996
Highly Cited
1996
Cells which are highly proliferative typically lack expression of differentiated, lineage-specific characteristics. Id2, a member… (More)
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Highly Cited
1994
Highly Cited
1994
Molecular interaction between transcription factors containing an basic-helix-loop-helix (bHLH) domain is known to regulate… (More)
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