ASCL1 protein, human

Known as: Human Achaete-Scute Homolog 1 Protein, bHLHa46, Class A Basic Helix-Loop-Helix Protein 46 
Achaete-scute homolog 1 (236 aa, ~25 kDa) is encoded by the human ASCL1 gene. This protein plays a role in both transcriptional regulation and signal… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Proneural genes such as Ascl1 are known to promote cell cycle exit and neuronal differentiation when expressed in neural… (More)
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Highly Cited
2007
Highly Cited
2007
The neural basic helix-loop-helix transcription factor Ascl1 (previously Mash1) is present in ventricular zone cells in… (More)
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Highly Cited
2007
Highly Cited
2007
The subventricular zone (SVZ) is the largest germinal zone in the mature rodent brain, and it continuously produces young neurons… (More)
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Highly Cited
2006
Highly Cited
2006
Sensory information from the periphery is integrated and transduced by excitatory and inhibitory interneurons in the dorsal… (More)
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Highly Cited
2004
Highly Cited
2004
The transcriptional control of the differentiation of central serotonergic (5-HT) neurons in vertebrates has recently come under… (More)
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Highly Cited
2001
Highly Cited
2001
Distinct classes of neurons are generated from progenitor cells distributed in characteristic dorsoventral patterns in the… (More)
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Highly Cited
2001
Highly Cited
2001
Recent studies have demonstrated that neural stem cells and other progenitors are present in the adult CNS. Details of their… (More)
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Highly Cited
2001
Highly Cited
2001
Previous analysis of mutant mice has revealed that the bHLH genes Mash1 and Math3, and the homeobox gene Chx10 are essential for… (More)
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Highly Cited
1998
Highly Cited
1998
Mash1, a mammalian homologue of the Drosophila proneural genes of the achaete-scute complex, is transiently expressed throughout… (More)
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Highly Cited
1997
Highly Cited
1997
The achaete-scute genes encode essential transcription factors in normal Drosophila and vertebrate nervous system development… (More)
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