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ASCL1 protein, human

Known as: Human Achaete-Scute Homolog 1 Protein, bHLHa46, Class A Basic Helix-Loop-Helix Protein 46 
Achaete-scute homolog 1 (236 aa, ~25 kDa) is encoded by the human ASCL1 gene. This protein plays a role in both transcriptional regulation and signal… 
National Institutes of Health

Related topics

Related topics

15 relations
ACSL1 GeneASCL1 GeneASCL1 wt AlleleCell Differentiation process

Broader (1)

Basic Helix-Loop-Helix Transcription Factors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Neurogenin 2 is required for the development of ventral midbrain dopaminergic neurons
Proneural genes are crucial regulators of neurogenesis and subtype specification in many areas of the nervous system; however… 
Highly Cited
2004
Highly Cited
2004
Altered Notch signaling resulting from expression of a WAMTP1-MAML2 gene fusion in mucoepidermoid carcinomas and benign Warthin's tumors.
Highly Cited
2004
Highly Cited
2004
Ascl1/Mash1 is required for the development of central serotonergic neurons
The transcriptional control of the differentiation of central serotonergic (5-HT) neurons in vertebrates has recently come under… 
Highly Cited
2001
Highly Cited
2001
A Role for the Helix-Loop-Helix Protein Id2 in the Control of Oligodendrocyte Development
Highly Cited
2001
Highly Cited
2001
Crossinhibitory Activities of Ngn1 and Math1 Allow Specification of Distinct Dorsal Interneurons
Highly Cited
2000
Highly Cited
2000
Hes genes regulate sequential stages of neurogenesis in the olfactory epithelium.
We have characterised the functions of the bHLH transcriptional repressors HES1 and HES5 in neurogenesis, using the development… 
Highly Cited
1999
Highly Cited
1999
Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality.
Notch family genes encode transmembrane proteins involved in cell-fate determination. Using gene targeting procedures, we… 
Highly Cited
1998
Highly Cited
1998
Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system.
Mash1, a mammalian homologue of the Drosophila proneural genes of the achaete-scute complex, is transiently expressed throughout… 
Review
1997
Review
1997
bHLH transcription factors and mammalian neuronal differentiation.
Highly Cited
1996
Highly Cited
1996
Mash1 promotes neuronal differentiation in the retina
Background: Mash1, a mammalian homologue of Drosophila achaete‐scute proneural gene complex, plays an essential role in… 
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