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ASCL1 protein, human

Known as: Human Achaete-Scute Homolog 1 Protein, bHLHa46, Class A Basic Helix-Loop-Helix Protein 46 
Achaete-scute homolog 1 (236 aa, ~25 kDa) is encoded by the human ASCL1 gene. This protein plays a role in both transcriptional regulation and signal… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
With the exception of astroglia-like cells in the neurogenic niches of the telencephalic subependymal or hippocampal subgranular… Expand
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Highly Cited
2001
Highly Cited
2001
We have addressed the role of the proneural bHLH genes Neurogenin2 (Ngn2) and Mash1 in the selection of neuronal and glial fates… Expand
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Highly Cited
2001
Highly Cited
2001
Among the various forms of human lung cancer, small cell lung cancer (SCLC) exhibits a characteristic neuroendocrine (NE… Expand
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Highly Cited
2000
Highly Cited
2000
Basic helix-loop-helix (bHLH) transcription factors are known to function during mammalian neurogenesis. Here we show that… Expand
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Highly Cited
2000
Highly Cited
2000
Neurogenin1 (Ngn1), Neurogenin2 (Ngn2), and Mash1 encode bHLH transcription factors with neuronal determination functions. In the… Expand
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Highly Cited
1999
Highly Cited
1999
Previous studies have shown that mice mutant for the gene Mash1 display severe neuronal losses in the olfactory epithelium and… Expand
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Highly Cited
1998
Highly Cited
1998
We have investigated the genetic circuitry underlying the determination of neuronal identity, using mammalian peripheral… Expand
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Highly Cited
1996
Highly Cited
1996
How growth factors influence the fate of multipotent progenitor cells is not well understood. Most hematopoietic growth factors… Expand
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Highly Cited
1993
Highly Cited
1993
The mouse Mash-1 gene, like its Drosophila homologs of the achaete-scute complex (AS-C), encodes a transcription factor expressed… Expand
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Highly Cited
1992
Highly Cited
1992
We report the molecular characterization of two novel rat helix-loop-helix (HLH) proteins, designated HES-1 and HES-3, that show… Expand
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