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ASCL1 protein, human
Known as:
Human Achaete-Scute Homolog 1 Protein
, bHLHa46
, Class A Basic Helix-Loop-Helix Protein 46
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Achaete-scute homolog 1 (236 aa, ~25 kDa) is encoded by the human ASCL1 gene. This protein plays a role in both transcriptional regulation and signal…
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National Institutes of Health
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Related topics
Related topics
15 relations
ACSL1 Gene
ASCL1 Gene
ASCL1 wt Allele
Cell Differentiation process
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Broader (1)
Basic Helix-Loop-Helix Transcription Factors
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
Neural bHLH Genes Control the Neuronal versus Glial Fate Decision in Cortical Progenitors
M. Nieto
,
C. Schuurmans
,
O. Britz
,
F. Guillemot
Neuron
2001
Corpus ID: 15254079
Highly Cited
2001
Highly Cited
2001
Notch signaling induces cell cycle arrest in small cell lung cancer cells.
V. Sriuranpong
,
M. Borges
,
+4 authors
D. Ball
Cancer Research
2001
Corpus ID: 12345190
Among the various forms of human lung cancer, small cell lung cancer (SCLC) exhibits a characteristic neuroendocrine (NE…
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Highly Cited
2000
Highly Cited
2000
Generation of neurons by transient expression of neural bHLH proteins in mammalian cells.
M. Farah
,
J. Olson
,
H. Sucic
,
R. Hume
,
S. Tapscott
,
D. Turner
Development
2000
Corpus ID: 2419189
Basic helix-loop-helix (bHLH) transcription factors are known to function during mammalian neurogenesis. Here we show that…
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Highly Cited
2000
Highly Cited
2000
A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons.
C. Fode
,
Q. Ma
,
S. Casarosa
,
S. Ang
,
D. Anderson
,
F. Guillemot
Genes & Development
2000
Corpus ID: 1552787
Neurogenin1 (Ngn1), Neurogenin2 (Ngn2), and Mash1 encode bHLH transcription factors with neuronal determination functions. In the…
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Highly Cited
1999
Highly Cited
1999
Mash1 regulates neurogenesis in the ventral telencephalon.
S. Casarosa
,
C. Fode
,
F. Guillemot
Development
1999
Corpus ID: 2384823
Previous studies have shown that mice mutant for the gene Mash1 display severe neuronal losses in the olfactory epithelium and…
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Highly Cited
1998
Highly Cited
1998
MASH1 activates expression of the paired homeodomain transcription factor Phox2a, and couples pan-neuronal and subtype-specific components of autonomic neuronal identity.
L. Lo
,
M. Tiveron
,
D. Anderson
Development
1998
Corpus ID: 14792808
We have investigated the genetic circuitry underlying the determination of neuronal identity, using mammalian peripheral…
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Highly Cited
1996
Highly Cited
1996
Alternative Neural Crest Cell Fates Are Instructively Promoted by TGFβ Superfamily Members
N. Shah
,
A. Groves
,
David J. Anderson
Cell
1996
Corpus ID: 11497323
Highly Cited
1993
Highly Cited
1993
Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons
F. Guillemot
,
L. Lo
,
Jane E. Johnson
,
A. Auerbach
,
David J. Anderson
,
A. Joyner
Cell
1993
Corpus ID: 19459236
Highly Cited
1992
Highly Cited
1992
Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split.
Y. Sasai
,
R. Kageyama
,
Y. Tagawa
,
R. Shigemoto
,
S. Nakanishi
Genes & Development
1992
Corpus ID: 35551715
We report the molecular characterization of two novel rat helix-loop-helix (HLH) proteins, designated HES-1 and HES-3, that show…
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Highly Cited
1991
Highly Cited
1991
Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells.
L. Lo
,
J. Johnson
,
C. Wuenschell
,
T. Saito
,
D. Anderson
Genes & Development
1991
Corpus ID: 18674284
Using monoclonal antibodies, we have examined the expression pattern of MASH1, a basic helix-loop-helix protein that is a…
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