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ASCL1 Gene

Known as: bHLHa46, HASH1, MAMMALIAN ACHAETE-SCUTE HOMOLOG 1 
This gene plays a role in neural development and regulation of transcription.
National Institutes of Health

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Related topics

6 relations
ASCL1 protein, humanHomo sapiensNeurogenesisTranscriptional Activation

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ASCL1 wt Allele

Papers overview

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2008
2008
Regulation of Prenatal Human Retinal Neurosphere Growth and Cell Fate Potential by Retinal Pigment Epithelium and Mash1
During development of the central nervous system, stem and progenitor cell proliferation and differentiation are controlled by… 
2006
2006
The bHLH transcription factors, Hes6 and Mash1, are expressed in distinct subsets of cells within adult mouse taste buds.
Taste buds are multicellular receptor organs embedded in the lingual epithelium of vertebrates. Taste cells within these buds are… 
Highly Cited
2004
Highly Cited
2004
Altered Notch signaling resulting from expression of a WAMTP1-MAML2 gene fusion in mucoepidermoid carcinomas and benign Warthin's tumors.
Highly Cited
2003
Highly Cited
2003
The role of human achaete-scute homolog-1 in medullary thyroid cancer cells.
Highly Cited
2003
Highly Cited
2003
Co-expression pattern of Shh with Prox1 and that of Nkx2.2 with Mash1 in mouse taste bud.
2001
2001
Downregulation of hASH1 is associated with the retinoic acid-induced differentiation of human neuroblastoma cell lines.
BACKGROUND MASH1, a transcription factor with basic helix-loop-helix domain, has a pivotal function to promote differentiation of… 
1996
1996
Functional and Physical Interactions between Mammalian Achaete-Scute Homolog 1 and Myocyte Enhancer Factor 2A*
The mammalian achaete-scute homolog 1 (MASH1) protein is required for the early development of the nervous system. However, the… 
Highly Cited
1996
Highly Cited
1996
Temporal and spatial pattern of MASH‐1 expression in the developing rat retina demonstrates progenitor cell heterogeneity
  • C. JasoniT. Reh
  • The Journal of comparative neurology
  • 1996
  • Corpus ID: 8617695
The temporal and spatial pattern of mammalian achaete‐scute homolog 1 (MASH‐1) expression in the developing rat retina was… 
Highly Cited
1996
Highly Cited
1996
Differentiation of medullary thyroid cancer by C-Raf-1 silences expression of the neural transcription factor human achaete-scute homolog-1.
1995
1995
Induction of a serotonergic and neuronal phenotype in thyroid C-cells
We have investigated whether rat thyroid C-cells can acquire a phenotype similar to serotonergic neurons. C-cells are neural… 
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