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Hereditary progressive dystonia with marked diurnal fluctuation caused by mutations in the GTP cyclohydrolase I gene
Hereditary progressive dystonia with marked diurnal fluctuation (HPD) (also known as dopa responsive dystonia) is a dystonia with onset in childhood that shows a marked response without any sideExpand
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miR‐145, miR‐133a and miR‐133b: Tumor‐suppressive miRNAs target FSCN1 in esophageal squamous cell carcinoma
MicroRNAs (miRNAs), noncoding RNAs 21–25 nucleotides in length, regulate gene expression primarily at the posttranscriptional level. Growing evidence suggests that miRNAs are aberrantly expressed inExpand
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Identification of novel microRNA targets based on microRNA signatures in bladder cancer
MicroRNAs (miRNAs) are small noncoding RNAs that negatively regulate protein‐coding genes. To identify miRNAs that have a tumor suppressive function in bladder cancer (BC), 156 miRNAs were screenedExpand
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Influence of hepatitis B virus genotypes on the progression of chronic type B liver disease
To investigate the hepatitis B virus (HBV) genotype‐related differences in the progression of liver disease, 585 patients with chronic HBV infection including 258 with histologically verified chronicExpand
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The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer
Background:On the base of the microRNA (miRNA) expression signature of bladder cancer (BC), we found that miR-1 and miR-133a were significantly downregulated in BC. In this study, we focussed on theExpand
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miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer
Background:We have recently identified down-regulated microRNAs including miR-145 and miR-133a in bladder cancer (BC). The aim of this study is to determine the genes targeted by miR-145, which isExpand
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Tumor suppressive microRNA-375 regulates oncogene AEG-1/MTDH in head and neck squamous cell carcinoma (HNSCC)
Our microRNA (miRNA) expression signatures of hypopharyngeal squamous cell carcinoma, maxillary sinus squamous cell carcinoma and esophageal squamous cell carcinoma revealed that miR-375 wasExpand
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Critical involvement of interferon γ in the pathogenesis of T‐cell activation‐associated hepatitis and regulatory mechanisms of interleukin‐6 for the manifestations of hepatitis
A single intravenous injection of concanavalin A (Con A) induces T‐cell activation and an acute hepatitis in mice. This study investigated the role of interferon γ (IFN‐γ) in the pathogenesis of thisExpand
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MiR‐96 and miR‐183 detection in urine serve as potential tumor markers of urothelial carcinoma: correlation with stage and grade, and comparison with urinary cytology
A new diagnostic marker for urothelial carcinoma (UC) is needed to avoid painful cystoscopy during the initial diagnosis and follow‐up period. However, the current urine markers are useless becauseExpand
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Gene expression of periostin in the early stage of fracture healing detected by cDNA microarray analysis
To comprehensively evaluate gene expression in the early stage of fracture healing, we used a cDNA microarray with 2304 cDNA clones derived from an oligo‐capped mouse embryo library. ClosedExpand
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