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BMP6 protein, human

Known as: Bone Morphogenetic Protein 6, bone morphogenetic protein 6, human, VG-1-R 
Bone morphogenetic protein 6 (513 aa, ~57 kDa) is encoded by the human BMP6 gene. This protein is involved in bone development.
National Institutes of Health

Related topics

Related topics

16 relations
BMP Receptor Signaling PathwayBMP6 geneBone Morphogenetic Protein GeneCell Differentiation process

Broader (1)

bone morphogenetic protein 6

Papers overview

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Highly Cited
2011
Highly Cited
2011
Regulation of TMPRSS6 by BMP6 and iron in human cells and mice.
Mutations in transmembrane protease, serine 6 (TMPRSS6), encoding matriptase-2, are responsible for the familial anemia disorder… 
Highly Cited
2010
Highly Cited
2010
Increased BMP6 Levels in the Brains of Alzheimer's Disease Patients and APP Transgenic Mice Are Accompanied by Impaired Neurogenesis
During aging and in the progression of Alzheimer's disease (AD), synaptic plasticity and neuronal integrity are disturbed. In… 
Highly Cited
2007
Highly Cited
2007
Reduced chondrogenic potential of adipose tissue derived stromal cells correlates with an altered TGFβ receptor and BMP profile and is overcome by BMP‐6
Recent interest has focused on mesenchymal stem cells (MSC) for tissue engineering and regenerative therapy of cartilage defects… 
Highly Cited
2007
Highly Cited
2007
Osteogenic Gene Expression by Human Periodontal Ligament Cells under Cyclic Tension
The forces that orthodontic appliances apply to the teeth are transmitted through the periodontal ligament (PDL) to the… 
Highly Cited
2006
Highly Cited
2006
Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse
Notch signaling is implicated in many developmental processes. In our current study, we have employed a transgenic strategy to… 
Highly Cited
2005
Highly Cited
2005
Oocytes prevent cumulus cell apoptosis by maintaining a morphogenic paracrine gradient of bone morphogenetic proteins
Paracrine factors secreted by the oocyte regulate a broad range of cumulus cell functions. Characteristically, cumulus cells have… 
Highly Cited
2005
Highly Cited
2005
Involvement of Endogenous Bone Morphogenetic Protein (BMP) 2 and BMP6 in Bone Formation*
Although accumulated evidence has shown the bone anabolic effects of bone morphogenetic proteins (BMPs) that were exogenously… 
Highly Cited
2001
Highly Cited
2001
Bmp6 and Bmp7 are required for cushion formation and septation in the developing mouse heart.
The mature heart valves and septa are derived from the cardiac cushions which initially form as local outgrowths of mesenchymal… 
Highly Cited
1999
Highly Cited
1999
Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast differentiation.
Bone morphogenetic protein (BMP)-6 is a member of the transforming growth factor (TGF)-(&bgr;) superfamily, and is most similar… 
Highly Cited
1991
Highly Cited
1991
Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse.
Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 are members of the TGF-beta gene family most closely related to the Drosophila… 
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