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BIRC3 gene

Known as: HIAP1, c-IAP2, BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 3 
This anti-apoptotic gene regulates apoptotic activity. BIRC3 gene promotes tumor cell survival.
National Institutes of Health

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6 relations
ApoptosisBIRC3 protein, humanInhibitor of Apoptosis 1 ProteinNegative Regulation of Apoptosis

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BIRC3 wt Allele

Papers overview

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2011
2011
Cucurbitacin B suppresses the transactivation activity of RelA/p65
Cucurbitacin B, a natural triterpenoid is well‐known for its strong anticancer activity, and recent studies showed that the… 
2010
2010
Abstract 2775: A phase I study of LCL161, an oral IAP inhibitor, in patients with advanced cancer
Introduction: LCL161 is a potent small molecule mimetic of the Smac mitochondrial protein. Like Smac, it binds to inhibitor of… 
2006
2006
cIAP2 is highly expressed in Hodgkin–Reed–Sternberg cells and inhibits apoptosis by interfering with constitutively active caspase-3
In this study, the expression of activated caspase-3 by the tumor cells of classical Hodgkin lymphoma (cHL), the Hodgkin–Reed… 
2004
2004
Antiapoptotic Function of Apoptosis Inhibitor 2-MALT1 Fusion Protein Involved in t(11;18)(q21;q21) Mucosa-Associated Lymphoid Tissue Lymphoma
t(11;18)(q21;q21) is a characteristic chromosomal translocation in mucosa-associated lymphoid tissue (MALT) type lymphoma, and… 
2004
2004
Mass spectrometric analysis of tumor necrosis factor receptor‐associated factor 1 ubiquitination mediated by cellular inhibitor of apoptosis 2
Signaling complexes formed on tumor necrosis factor receptor 2 (TNF‐R2) contain adaptor proteins TNF‐R‐associated factors (TRAFs… 
2004
2004
Common threads of mucosa-associated lymphoid tissue lymphoma pathogenesis: from infection to translocation.
In this issue of the Journal, Ferreri et al. (1) add to the growing list of infectious agents that have been associated with… 
2000
2000
Tumor necrosis factor-alpha-induced lung cell expression of antiapoptotic genes TRAF1 and cIAP2.
Tumor necrosis factor (TNF) receptor (TNFR)-associated factors 1 and 2 (TRAF1 and TRAF2) and inhibitor of apoptosis proteins… 
1999
1999
Genomic organization and physical map of the human inhibitors of apoptosis: HIAP1 and HIAP2
Abstract. We report the genomic organization, mapping, and tissue distribution of the human inhibitors of apoptosis, HIAP1 and… 
1997
1997
Genomic organization and primary characterization of miap-3: the murine homologue of human X-linked IAP.
IAPs (inhibitor of apoptosis proteins) are a recently identified family of proteins that function in the cell death pathway to… 
Highly Cited
1989
Highly Cited
1989
Partial deduced sequence of the 110-kD-calmodulin complex of the avian intestinal microvillus shows that this mechanoenzyme is a member of the myosin I family
The actin bundle within each microvillus of the intestinal brush border is laterally tethered to the membrane by bridges composed… 
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