BIRC3 gene

Known as: HIAP1, c-IAP2, BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 3 
This anti-apoptotic gene regulates apoptotic activity. BIRC3 gene promotes tumor cell survival.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2018
010203019852018

Papers overview

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Highly Cited
2012
Highly Cited
2012
The genetic lesions identified to date do not fully recapitulate the molecular pathogenesis of chronic lymphocytic leukemia (CLL… (More)
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Highly Cited
2011
Highly Cited
2011
A better understanding of the mechanisms through which anticancer drugs exert their effects is essential to improve combination… (More)
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Highly Cited
2011
Highly Cited
2011
Three members of the IAP family (X-linked inhibitor of apoptosis (XIAP), cellular inhibitor of apoptosis proteins-1/-2 (cIAP1 and… (More)
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Highly Cited
2011
Highly Cited
2011
Splenic marginal zone lymphoma (SMZL) is one of the few B-cell lymphoma types that remain orphan of molecular lesions in cancer… (More)
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Highly Cited
2008
Highly Cited
2008
The inflammatory response of mammalian cells to TNF-alpha can be switched to apoptosis either by cotreatment with a protein… (More)
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Highly Cited
2008
Highly Cited
2008
The inhibitor of apoptosis (IAP) family of proteins enhances cell survival through mechanisms that remain uncertain. In this… (More)
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Highly Cited
2000
Highly Cited
2000
To identify proteins that bind mammalian IAP homolog A (MIHA, also known as XIAP), we used coimmuno-precipitation and 2D… (More)
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Highly Cited
2000
Highly Cited
2000
The inhibitor of apoptosis, cIAP2, contains a putative Ring finger motif at the C terminus. Using in vitro ubiquitination assays… (More)
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Highly Cited
1999
Highly Cited
1999
Marginal zone cell lymphomas of the mucosa-associated lymphoid tissue (MALT) are the most common subtype of lymphoma arising at… (More)
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Highly Cited
1996
Highly Cited
1996
Baculovirus inhibitors of apoptosis (IAPs) act in insect cells to prevent cell death. Here we describe three mammalian homologs… (More)
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