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BIRC3 wt Allele

Known as: HIAP1, Baculoviral IAP Repeat-Containing 3 wt Allele, Apoptosis Inhibitor 2 Gene 
Human BIRC3 wild-type allele is located in the vicinity of 11q25 and is approximately 14 kb in length. This allele, which encodes baculoviral IAP… 
National Institutes of Health

Related topics

Related topics

9 relations
11q22-q23ApoptosisBIRC3 protein, humanCaspase Cascade Pathway

Broader (1)

BIRC3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2020
Highly Cited
2020
Multiplex immunohistochemistry/immunofluorescence (mIHC/IF) for PD-L1 testing in triple-negative breast cancer: a translational assay compared with conventional IHC
Background Programmed death-ligand 1 (PD-L1) monoclonal antibody therapy has recently gained approval for treating metastatic… 
2019
2019
Ubiquitin Ligases cIAP1 and cIAP2 Limit Cell Death to Prevent Inflammation.
Highly Cited
2018
Highly Cited
2018
Multiplex immunohistochemistry accurately defines the immune context of metastatic melanoma
A prospective study explored the heterogeneous nature of metastatic melanoma using Multiplex immunohistochemistry (IHC) and flow… 
Highly Cited
2013
Highly Cited
2013
The Novel SMAC Mimetic Birinapant Exhibits Potent Activity against Human Melanoma Cells
Purpose: Inhibitor of apoptosis proteins (IAP) promote cancer cell survival and confer resistance to therapy. We report on the… 
Highly Cited
2011
Highly Cited
2011
Molecular determinants of Smac mimetic induced degradation of cIAP1 and cIAP2
The inhibitors of apoptosis (IAP) proteins cIAP1 and cIAP2 have recently emerged as key ubiquitin-E3 ligases regulating innate… 
Highly Cited
2008
Highly Cited
2008
The RING domain of cIAP1 mediates the degradation of RING-bearing inhibitor of apoptosis proteins by distinct pathways.
The Inhibitor of Apoptosis proteins (IAPs) are key repressors of apoptosis. Several IAP proteins contain a RING domain that… 
2006
2006
cIAP2 is highly expressed in Hodgkin–Reed–Sternberg cells and inhibits apoptosis by interfering with constitutively active caspase-3
In this study, the expression of activated caspase-3 by the tumor cells of classical Hodgkin lymphoma (cHL), the Hodgkin–Reed… 
2005
2005
IAPs – the ubiquitin connection
One way or another, almost all proteins containing baculoviralIAP repeat domains (BIRs) have been associated withubiquitin (the… 
Highly Cited
2002
Highly Cited
2002
Cytokine regulation of pro- and anti-apoptotic genes in rat hepatocytes: NF-kappaB-regulated inhibitor of apoptosis protein 2 (cIAP2) prevents apoptosis.
2001
2001
Analysis of candidate antagonists of IAP-mediated caspase inhibition using yeast reconstituted with the mammalian Apaf-1-activated apoptosis mechanism
We have reconstituted the Apaf-1-activated apoptosis mechanism in Sacchromyces cerevisiae such that the presence of a… 
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