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BIRC2 wt Allele

Known as: MIHB, API1, Mammalian IAP Homolog B 
Human BIRC2 wild-type allele is located in the vicinity of 11q22 and is approximately 30 kb in length. This allele, which encodes baculoviral IAP… 
National Institutes of Health

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11q22ApoptosisBIRC2 geneBIRC2 protein, human

Papers overview

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2019
2019
Expression and Relationship of SAMHD1 with Other Apoptotic and Autophagic Genes in Acute Myeloid Leukemia Patients
Background: SAM domain- and HD domain-containing protein 1 (SAMHD1) is a cellular enzyme which is responsible for blocking… 
2014
2014
A novel role for inhibitor of apoptosis (IAP) proteins as regulators of endothelial barrier function by mediating RhoA activation
Inhibitor of apoptosis (IAP) proteins, such as XIAP or cIAP1/2, are important regulators of apoptosis in cancer cells, and IAP… 
2013
2013
Physiologically based pharmacokinetic and pharmacodynamic modeling of an antagonist (SM‐406/AT‐406) of multiple inhibitor of apoptosis proteins (IAPs) in a mouse xenograft model of human breast…
The inhibitors of apoptosis proteins (IAPs) are a class of key apoptosis regulators overexpressed or dysregulated in cancer. SM… 
2012
2012
Discovery of aminopiperidine-based Smac mimetics as IAP antagonists.
2011
2011
The tyrphostin AG1478 inhibits proliferation and induces death of liver tumor cells through EGF receptor-dependent and independent mechanisms.
2010
2010
Tumor Necrosis Factor (TNF) Signaling, but Not TWEAK (TNF-like Weak Inducer of Apoptosis)-triggered cIAP1 (Cellular Inhibitor of Apoptosis Protein 1) Degradation, Requires cIAP1 RING Dimerization and…
Cellular inhibitor of apoptosis (cIAP) proteins, cIAP1 and cIAP2, are important regulators of tumor necrosis factor (TNF… 
2009
2009
Expression patterns and prognostic significance of inhibitor of apoptosis proteins in adenoid cystic carcinoma and pleomorphic adenoma of lachrymal gland.
2008
2008
Expression and distributional patterns of the inhibitor of apoptosis protein family and caspase 3 in nasal polyps.
OBJECTIVES To investigate the expression and distributional patterns of the inhibitor of apoptosis protein (IAP) family and… 
2006
2006
Inhibition of apoptosis by Nur77 through NF-kappaB activity modulation.
The orphan nuclear receptor Nur77 has been described as a mediator of apoptosis and has also been associated with growth… 
2005
2005
IAPs – the ubiquitin connection
One way or another, almost all proteins containing baculoviralIAP repeat domains (BIRs) have been associated withubiquitin (the… 
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