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  • Emina Huang, Mark J. Hynes, +6 authors Bruce M Boman
  • Biology, Medicine
  • Cancer research
  • 2009 (First Publication: 7 April 2009)
  • Although the concept that cancers originate from stem cells (SC) is becoming scientifically accepted, mechanisms by which SC contribute to tumor initiation and progression are largely unknown. ForContinue Reading
  • Qian Cai, Haiying Sun, +15 authors Shaomeng Wang
  • Chemistry, Medicine
  • Journal of medicinal chemistry
  • 2011 (First Publication: 28 April 2011)
  • We report the discovery and characterization of SM-406 (compound 2), a potent and orally bioavailable Smac mimetic and an antagonist of the inhibitor of apoptosis proteins (IAPs). This compound bindsContinue Reading
  • Tao Zhang, Cathie Dong Xiang, David C. Gale, Samantha T Carreiro, Ellen Y. Wu, Eric Y. Zhang
  • Medicine, Biology
  • Drug metabolism and disposition: the biological…
  • 2008 (First Publication: 1 July 2008)
  • Studies were designed to quantitatively assess the mRNA expression of 1) 10 cytochrome P450 (P450) enzymes in human cornea, iris-ciliary body (ICB), and retina/choroid relative to their levels in theContinue Reading
  • Hongyun Wang, Nicole C. McKnight, Tao Zhang, Michael L. Lu, Steven P. Balk, Xin Yuan
  • Biology, Medicine
  • Cancer research
  • 2007 (First Publication: 15 January 2007)
  • SOX9 is a member of the SOX [Sry-related high-mobility group (HMG) box] family of HMG DNA-binding domain transcription factors and is required for the development and differentiation of multiple cellContinue Reading
    Effects of stocking density on seston dynamics and filtering and biodeposition by the suspension-cultured Zhikong scallop Chlamys farreri Jones et Preston in a eutrophic bay (Sishili Bay, northernContinue Reading