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BIK gene

Known as: BCL2-INTERACTING KILLER, natural born killer, NBK 
This gene is involved in the regulation of apoptosis and induces apoptotic activity.
National Institutes of Health

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Related topics

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ApoptosisBCL2-Interacting KillerPositive Regulation of Apoptosis

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BIK wt Allele

Papers overview

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Highly Cited
2019
Highly Cited
2019
Gene Amplification-Driven Long Noncoding RNA SNHG17 Regulates Cell Proliferation and Migration in Human Non-Small-Cell Lung Cancer
2017
2017
Differing Mechanisms of Death Induction by Fluorinated Taxane SB-T-12854 in Breast Cancer Cells.
BACKGROUND/AIM Classical taxanes are routinely used in cancer therapy. In this study, mechanisms involved in death induction by… 
2015
2015
Nucleobase modified neamines with a lysine as a linker, their inhibition specificity for TAR-Tat derived from HIV-1.
2014
2014
Participación de la proteína BIK en los procesos apoptóticos
Cell death (apoptosis) is a process relevant in the development and differentiation of multicellular organism and its alterations… 
2009
2009
BAK, BAX, and NBK/BIK Proapoptotic Gene Alterations in Iranian Patients with Ataxia Telangiectasia
IntroductionAtaxia telangiectasia (AT) is an autosomal recessive multisystem disorder characterized by variable immunodeficiency… 
Highly Cited
2007
Highly Cited
2007
Apoptosis-based dual molecular targeting by INNO-406, a second-generation Bcr-Abl inhibitor, and ABT-737, an inhibitor of antiapoptotic Bcl-2 proteins, against Bcr-Abl-positive leukemia
Bcr-Abl is the cause of Philadelphia-positive (Ph+) leukemias and also constitutes their principal therapeutic target, as… 
Review
2007
Review
2007
Overview of Microarray Analysis of Gene Expression and its Applications to Cervical Cancer Investigation
2005
2005
Caspase-independent induction of apoptosis in human melanoma cells by the proapoptotic Bcl-2-related protein Nbk / Bik
The proapoptotic BH3-only protein natural born killer / Bcl-2 interacting killer (Nbk / Bik) has been described to inhibit Bcl-2… 
2002
2002
Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death.
The anti-apoptotic effect of a chloride-bicarbonate exchange blocker has been previously examined in endothelial cells and… 
Highly Cited
2001
Highly Cited
2001
Involvement of Bik, a Proapoptotic Member of the Bcl-2 Family, in Surface IgM-Mediated B Cell Apoptosis1
Apoptosis plays a central role in shaping the repertoire of circulating mature B lymphocytes, but the underlying molecular… 
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