Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

BARD1 gene

Known as: BRCA1 Associated RING Domain 1 Gene, BARD1, BRCA1 associated RING domain 1 
This gene plays a role in cellular response and is susceptible to oncogenic mutations in breast and ovarian cancers.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
BACKGROUND Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy, responsible for 13 000 deaths per year in… Expand
Is this relevant?
Highly Cited
2013
Highly Cited
2013
Neuroblastoma is a malignancy of the developing sympathetic nervous system that often presents with widespread metastatic disease… Expand
  • figure 1
  • figure 2
  • table 1
  • table 2
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Fifteen years ago BRCA1 and BRCA2 were reported as high penetrant breast cancer predisposing genes. However, mutations in these… Expand
Is this relevant?
Highly Cited
2009
Highly Cited
2009
We conducted a SNP-based genome-wide association study (GWAS) focused on the high-risk subset of neuroblastoma. As our previous… Expand
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Inherited germline mutations in the tumor suppressor gene BRCA1 predispose individuals to early onset breast and ovarian cancer… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Repair of chromosomal breaks is essential for cellular viability, but misrepair generates mutations and gross chromosomal… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
BRCA1 is a breast and ovarian cancer tumor suppressor protein that associates with BARD1 to form a RING/RING heterodimer. The… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Germline alterations of BRCA1 result in susceptibility to breast and ovarian cancer. The protein encoded by BRCA1 interacts in… Expand
  • table 1
  • table 2
  • table 3
  • figure 1
  • figure 3
Is this relevant?
Highly Cited
1997
Highly Cited
1997
BRCA1 localizes to discrete nuclear foci (dots) during S phase. Hydroxyurea-mediated DNA synthesis arrest of S phase MCF7 cells… Expand
  • figure 1
  • figure 3
  • figure 4
  • figure 5
  • figure 6
Is this relevant?
Highly Cited
1996
Highly Cited
1996
The hereditary breast and ovarian cancer gene, BRCA1, encodes a large polypeptide that contains the cysteine–rich RING motif, a… Expand
Is this relevant?