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Aspartic Acid Proteases

Known as: Aspartic Acid Proteinases, Aspartic Proteinases, Aspartic Acid Proteases [Chemical/Ingredient] 
Aspartyl Proteases (Aspartic Endopeptidases) have an acidic residue (aspartate) involved in the catalytic process, have a pH optimum below 5 and… 
National Institutes of Health

Related topics

Related topics

19 relations
Aspartic Acid EndopeptidasesBACE1 protein, humanBeta-Secretase 2, humanCATHEPSIN D

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Identification of hot spots within druggable binding regions by computational solvent mapping of proteins.
Here we apply the computational solvent mapping (CS-Map) algorithm toward the in silico identification of hot spots, that is… 
Highly Cited
1999
Highly Cited
1999
Germ Tubes and Proteinase Activity Contribute to Virulence of Candida albicans in Murine Peritonitis
ABSTRACT Peritonitis with Candida albicans is an important complication of bowel perforation and continuous ambulatory peritoneal… 
Highly Cited
1998
Highly Cited
1998
Rapid Detection of Candida albicans in Clinical Samples by DNA Amplification of Common Regions from C. albicans-Secreted Aspartic Proteinase Genes
ABSTRACT Laboratory diagnosis based on genomic amplification methods such as PCR may provide an alternative and more sensitive… 
Highly Cited
1997
Highly Cited
1997
A novel protein with DNA binding activity from tobacco chloroplast nucleoids.
A 41-kD DNA binding protein with a basic pl was purified from chloroplast nucleoids in photomixotrophically cultured tobacco… 
Highly Cited
1996
Highly Cited
1996
Molecular cloning of a tomato leaf cDNA encoding an aspartic protease, a systemic wound response protein
A full-length cDNA encoding an aspartic protease (LeAspP) has been cloned from a tomato leaf cDNA library. Using LeAspP cDNA as a… 
Review
1992
Review
1992
Age Dependence of Ischaemic Heart Syndromes and the Contribution of Haemostatic Deviations
Review
1992
Review
1992
Cathepsin D in the malignant progression of neoplastic diseases (review).
Recent studies suggest that aspartic proteinase Cathepsin D may be implicated in the process of tumor invasion and metastasis. In… 
Highly Cited
1988
Highly Cited
1988
Primary structure of human pepsinogen C gene.
Highly Cited
1985
Highly Cited
1985
Pepstatin-derived inhibitors of aspartic proteinases. A close look at an apparent transition-state analogue inhibitor.
Highly Cited
1982
Highly Cited
1982
Conformational flexibility in the active sites of aspartyl proteinases revealed by a pepstatin fragment binding to penicillopepsin.
Crystals of the molecular complex between the esterified tripeptide fragment of pepstatin and the aspartyl proteinase… 
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