Apolipoprotein E3

Known as: APOE epsilon 3, Isoapolipoprotein E3, APOE epsilon3 
A 34-kDa glycosylated protein. A major and most common isoform of apolipoprotein E. Therefore, it is also known as apolipoprotein E (ApoE). In human… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1980-2017
0204019802017

Papers overview

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Highly Cited
2012
Highly Cited
2012
Human apolipoprotein E has three isoforms: APOE2, APOE3 and APOE4. APOE4 is a major genetic risk factor for Alzheimer’s disease… (More)
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Highly Cited
2002
Highly Cited
2002
Nitric oxide (NO) derived from endothelial NO synthase (eNOS) is regarded as a protective factor against atherosclerosis… (More)
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Highly Cited
1999
Highly Cited
1999
Apolipoprotein (apo) E isoforms are key determinants of susceptibility to Alzheimer's disease. The apoE4 isoform is the major… (More)
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Highly Cited
1999
Highly Cited
1999
The epsilon4 allele of apolipoprotein E (apo E) is associated with an increased risk for developing Alzheimer's disease (AD… (More)
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Highly Cited
1998
Highly Cited
1998
The molecular mechanisms of hypertriglyceridemia (HTG), a common lipid metabolic disorder in humans, often of genetic origin, are… (More)
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Highly Cited
1995
Highly Cited
1995
Previously, we demonstrated in cultured dorsal root ganglion neurons that, in the presence of beta-migrating very low density… (More)
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Highly Cited
1994
Highly Cited
1994
Apolipoprotein E4 (apoE4), one of the three common isoforms of apoE, has been implicated in Alzheimer's disease. The effects of… (More)
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Highly Cited
1994
Highly Cited
1994
Human apolipoprotein (apo) E4 (arginine at residue 112) preferentially associates with very low density lipoproteins (VLDL), and… (More)
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Highly Cited
1993
Highly Cited
1993
Amyloid beta-peptide (A beta) deposition in senile plaques and cerebral vessels is a neuropathological feature of Alzheimer… (More)
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Highly Cited
1986
Highly Cited
1986
Apolipoprotein E (apoE) is important in modulating the catabolism of remnants of triglyceride-rich lipoprotein particles. It is a… (More)
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