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Apolipoprotein E3

Known as: APOE epsilon 3, Isoapolipoprotein E3, APOE epsilon3 
A 34-kDa glycosylated protein. A major and most common isoform of apolipoprotein E. Therefore, it is also known as apolipoprotein E (ApoE). In human… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Human apolipoprotein E has three isoforms: APOE2, APOE3 and APOE4. APOE4 is a major genetic risk factor for Alzheimer’s disease… Expand
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Highly Cited
2011
Highly Cited
2011
Human apolipoprotein E (apoE) is one of the major determinants in lipid transport, playing a critical role in atherosclerosis and… Expand
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Highly Cited
2004
Highly Cited
2004
Abstract LRP (low-density lipoprotein receptor-related protein) is linked to Alzheimer's disease (AD). Here, we report amyloid… Expand
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Review
2000
Review
2000
First recognized as a major determinant in lipoprotein metabolism and cardiovascular disease, apolipoprotein (apo) E has emerged… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND The epsilon4 allele of the apolipoprotein E gene (APOE) is the chief known genetic risk factor for Alzheimer's disease… Expand
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Highly Cited
1999
Highly Cited
1999
Apolipoprotein (apo) E isoforms are key determinants of susceptibility to Alzheimer’s disease. The apoE4 isoform is the major… Expand
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Highly Cited
1997
Highly Cited
1997
A role for β-amyloid precursor protein (β-APP) in the development of Alzheimer's disease has been indicated by genetics, and many… Expand
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Highly Cited
1994
Highly Cited
1994
Apolipoprotein E4 (apoE4), one of the three common isoforms of apoE, has been implicated in Alzheimer's disease. The effects of… Expand
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Highly Cited
1993
Highly Cited
1993
Amyloid beta-peptide (A beta) deposition in senile plaques and cerebral vessels is a neuropathological feature of Alzheimer… Expand
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Highly Cited
1993
Highly Cited
1993
Apolipoprotein E (apoE), a plasma apolipoprotein that plays a central role in lipoprotein metabolism, is localized in the senile… Expand
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