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Apolipoprotein E
Known as:
Apolipoproteins E
, Apolipoproteins E [Chemical/Ingredient]
, Apo E
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A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and…
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National Institutes of Health
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Related topics
Related topics
34 relations
APOE gene
Alzheimer's Disease
Alzheimer's Disease Pathway KEGG
Apolipoprotein E phenotyping:Prid:Pt:Bld:Nom
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Narrower (7)
Apolipoprotein E Isoproteins
Apolipoprotein E2
COG1410
apolipoprotein E1
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Broader (2)
Apolipoproteins
Apoproteins E
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2000
Review
2000
Apolipoprotein E: far more than a lipid transport protein.
R. Mahley
,
S. C. Rall
Annual review of genomics and human genetics…
2000
Corpus ID: 24134958
First recognized as a major determinant in lipoprotein metabolism and cardiovascular disease, apolipoprotein (apo) E has emerged…
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Highly Cited
1997
Highly Cited
1997
Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease: A Meta-analysis
L. Farrer
,
L. Cupples
,
+7 authors
C. Duijn
1997
Corpus ID: 51386222
Objective. —To examine more closely the association between apolipoprotein E (APOE) genotype and Alzheimer disease (AD) by age…
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Highly Cited
1997
Highly Cited
1997
Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium.
L. Farrer
,
L. Cupples
,
+7 authors
C. Duijn
Journal of the American Medical Association (JAMA…
1997
Corpus ID: 26079394
OBJECTIVE To examine more closely the association between apolipoprotein E (APOE) genotype and Alzheimer disease (AD) by age and…
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Highly Cited
1994
Highly Cited
1994
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease
E. Corder
,
A. Saunders
,
+11 authors
M. Pericak-Vance
Nature Genetics
1994
Corpus ID: 11137478
Gene dosage of the apolipoprotein E (APOE) ε4 allele is a major risk factor for familial Alzheimer disease (AD) of late onset…
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Highly Cited
1993
Highly Cited
1993
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families.
E. Corder
,
A. Saunders
,
+6 authors
M. Pericak-Vance
Science
1993
Corpus ID: 22880271
The apolipoprotein E type 4 allele (APOE-epsilon 4) is genetically associated with the common late onset familial and sporadic…
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Highly Cited
1993
Highly Cited
1993
Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.
W. Strittmatter
,
A. Saunders
,
+4 authors
A. Roses
Proceedings of the National Academy of Sciences…
1993
Corpus ID: 20937018
Apolipoprotein E is immunochemically localized to the senile plaques, vascular amyloid, and neurofibrillary tangles of Alzheimer…
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Highly Cited
1993
Highly Cited
1993
Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease.
A. Saunders
,
W. Strittmatter
,
+7 authors
M. Alberts
Neurology
1993
Corpus ID: 23148201
Apolipoprotein E, type epsilon 4 allele (APOE epsilon 4), is associated with late-onset familial Alzheimer's disease (AD). There…
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Highly Cited
1992
Highly Cited
1992
Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E.
Sunny H. Zhang
,
R. Reddick
,
J. Piedrahita
,
N. Maeda
Science
1992
Corpus ID: 33837863
Apolipoprotein E (apoE) is a ligand for receptors that clear remnants of chylomicrons and very low density lipoproteins. Lack of…
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Highly Cited
1990
Highly Cited
1990
Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI.
J. Hixson
,
D. T. Vernier
Journal of Lipid Research
1990
Corpus ID: 22607208
We have used restriction isotyping (restriction enzyme isoform genotyping) for rapid typing of common apolipoprotein E isoforms…
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Review
1988
Review
1988
Apolipoprotein E: cholesterol transport protein with expanding role in cell biology.
R. Mahley
Science
1988
Corpus ID: 39056805
Apolipoprotein E is a plasma protein that serves as a ligand for low density lipoprotein receptors and, through its interaction…
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