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Apolipoprotein E (Apo-E) is a major cholesterol carrier that supports lipid transport and injury repair in the brain. APOE… Expand Objective. —To examine more closely the association between apolipoprotein E (APOE) genotype and Alzheimer disease (AD) by age… Expand The apolipoprotein E type 4 allele (APOE-epsilon 4) is genetically associated with the common late onset familial and sporadic… Expand Apolipoprotein E is immunochemically localized to the senile plaques, vascular amyloid, and neurofibrillary tangles of Alzheimer… Expand Apolipoprotein E, type ϵ4 allele (APOE ϵ4), is associated with late-onset familial Alzheimer's disease (AD). There is high… Expand Apolipoprotein E (apoE) is a ligand for receptors that clear remnants of chylomicrons and very low density lipoproteins. Lack of… Expand apoE-deficient mice have been created by homologous recombination in ES cells. On a low fat, low cholesterol chow diet these… Expand We have used restriction isotyping (restriction enzyme isoform genotyping) for rapid typing of common apolipoprotein E isoforms… Expand Apolipoprotein E is a plasma protein that serves as a ligand for low density lipoprotein receptors and, through its interaction… Expand The apo E locus contributes to determining the variation in plasma cholesterol levels of healthy and diseased populations. It… Expand