COG1410
National Institutes of Health
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Vision loss after traumatic optic nerve injury (TONI) is considered irreversible because of the retrograde loss of retinal…
TTP TTP P Tristetraprolin (TTP), a key negative regulator of proinflammatory cytokine production, could be a novel therapeutic…
After age, the APOE4 genotype is the largest risk factor for Alzheimer’s disease (AD). We have developed a series of novel “COG…
Traumatic axonal injury (TAI) accounts for at least 35% of the morbidity and mortality in traumatic brain injury (TBI) patients…
animals that received the ApoE3 mimetics COG112 and COG1410 made less of the proinflammatory cytokine interleukin 6, lost fewer…
Using model of focal brain ischemia in males of CD rats, neuroprotective properties of peptide COG1410, with sequence of ApoE…
We have previously shown that a single dose of COG1410, a small molecule ApoE-mimetic peptide derived from the apolipoprotein E…