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Apamin

Known as: Apamin [Chemical/Ingredient] 
A highly neurotoxic polypeptide from the venom of the honey bee (Apis mellifera). It consists of 18 amino acids with two disulfide bridges and causes… 
National Institutes of Health

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10 relations

Narrower (2)

4-azido-2-nitrophenylaminoacetylmonoiodoapaminmonoiodoapamin
In BloodProcess of secretionagonistsanalogs & derivatives

Papers overview

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Review
2005
Review
2005
SK channels in excitability, pacemaking and synaptic integration
Highly Cited
1999
Highly Cited
1999
An apamin-sensitive Ca2+-activated K+ current in hippocampal pyramidal neurons.
In hippocampal and other cortical neurons, action potentials are followed by afterhyperpolarizations (AHPs) generated by the… 
Highly Cited
1999
Highly Cited
1999
Enhancement of bistability in spinal motoneurons in vivo by the noradrenergic alpha1 agonist methoxamine.
Enhancement of bistability in spinal motoneurons in vivo by the noradrenergic alpha1 agonist methoxamine. Like many types of… 
Highly Cited
1997
Highly Cited
1997
Determinants of Apamin and d-Tubocurarine Block in SK Potassium Channels*
Small conductance calcium-activated potassium channels show a distinct pharmacology. Some, but not all, are blocked by the… 
Highly Cited
1991
Highly Cited
1991
Ca2+-activated K+ currents underlying the afterhyperpolarization in guinea pig vagal neurons: A role for Ca2+-activated Ca2+ release
Review
1989
Review
1989
Toxins in the characterization of potassium channels
Highly Cited
1989
Highly Cited
1989
A family of calcium-dependent potassium channels from rat brain
Highly Cited
1988
Highly Cited
1988
ATP-sensitive K+ channels that are blocked by hypoglycemia-inducing sulfonylureas in insulin-secreting cells are activated by galanin, a hyperglycemia-inducing hormone.
The action of the hyperglycemia-inducing hormone galanin, a 29-amino acid peptide named from its N-terminal glycine and C… 
Highly Cited
1981
Highly Cited
1981
Effects of quinine and apamin on the calcium‐dependent potassium permeability of mammalian hepatocytes and red cells.
1. K‐sensitive electrodes placed in the extracellular fluid have been used to show that ATP and noradrenaline cause a rapid loss… 
Highly Cited
1979
Highly Cited
1979
Apamin blocks certain neurotransmitter-induced increases in potassium permeability
Apamin1 is a neurotoxic polypeptide of known structure2,3 isolated from bee venom. Shuba and coworkers4,5 have recently shown… 
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