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Evidence for a modulatory role of Ih on the firing of a subgroup of midbrain dopamine neurons
TLDR
It is concluded that the hyperpolarization-activated cation current Ih controls to a certain extent the firing of a majority of midbrain dopaminergic neurons. Expand
Cognitive impairment, dementia and quality of life in patients and caregivers.
TLDR
It is suggested that improving the cognitive status of patients and providing assistance to caregivers would be complementary ways of action to support caregiving of patients living at home. Expand
Evidence for the presence of N-methyl-d-aspartate receptors in the ventral tegmental area of the rat: an electrophysiological in vitro study
TLDR
The observations of spontaneously active, presumed dopaminergic neurons of the ventral tegmental area of the rat in a slice preparation strongly support the presence of specific NMDA receptors in the VTA. Expand
A new approach to the qualitative evaluation of functional disability in dementia
TLDR
In order to differentiate between mild, moderate and severe patients both instrumental and basic functional disabilities should be taken into account simultaneously. Expand
Hydrogen peroxide hyperpolarizes rat CA1 pyramidal neurons by inducing an increase in potassium conductance
TLDR
It is suggested that hydrogen peroxide is able to induce an increase in potassium conductance in rat CA1 pyramidal neurons through hyperpolarization, and the exact mechanism by which it produces this effect remains to be determined. Expand
The economic impact of dementia in Belgium: results of the National Dementia Economic Study (NADES).
TLDR
A large fraction of the costs observed in dementia is explained by the association of dementia with physical dependence, co-morbidity and need for caregiving, and the results support the caring for patients at home. Expand
Galanin decreases the activity of locus coeruleus neurons in vitro.
TLDR
Experiments performed in low-Ca2+, high-Mg2+ medium also showed a significant inhibition by galanin (10(-7) M) in three out of five neurons, which suggests that the peptide acts directly. Expand
Evidence for a non-GABAergic action of quaternary salts of bicuculline on dopaminergic neurones
TLDR
The results strongly suggest that quaternary salts of bicuculline act on more than one target in the central nervous system, and the involvement of GABA(A) receptors in a given effect cannot be proven solely on the basis of its blockade by these agents. Expand
Electrophysiological effects of neurotensin on dopaminergic neurones of the ventral tegmental area of the rat in vitro
TLDR
The results show that neurotensin potently activates presumed dopaminergic neurones in the ventral tegmental area in vitro; it may also decrease the effectiveness of the autoreceptors of some neurones. Expand
Effect of intermittent and continuous exposure to electromagnetic fields on cultured hippocampal cells.
TLDR
Although the effects of IEMFs reported in this study were only observed at very high intensities, the model may prove valuable in trying to identify one cellular target of EMFs. Expand
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