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Antipain

Known as: Antipain [Chemical/Ingredient], L-Valinamide, N2-(((1-carboxy-2-phenylethyl)amino)carbonyl)-L-arginyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)- 
An oligopeptide produced by various bacteria which acts as a protease inhibitor.
National Institutes of Health

Related topics

Related topics

11 relations
In BloodProcess of secretionagonistsanalogs & derivatives

Broader (1)

Protease Inhibitors

Narrower (1)

phenylalanyl-ureido-citrullinyl-valinyl-cycloarginal

Papers overview

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1985
1985
Antipain-mediated suppression of sister chromatid exchanges induced by an inhibitor of poly (ADP-ribose) polymerase.
Exposure of mammalian cells to inhibitors of poly(ADP-ribose) polymerase, such as 3-aminobenzamide (3AB) results in the induction… 
1985
1985
Non-histone chromosomal protein acceptors for poly(ADP)-ribose in phorbol-12-myristate-13-acetate treated mouse embryo fibroblasts (C3H10T1/2).
The tumor promoter phorbol-12-myristate-13-acetate (PMA) increases the level of poly ADP-ribosylation of chromosomal proteins in… 
1983
1983
Antiteratogenic effects of tumor inhibitors, caffeine, antipain, and retinoic acid in mice.
To learn the effects of tumor inhibitors on chemically induced malformations, caffeine, antipain, and 13-trans-retinoic acid were… 
1980
1980
Antipain inhibits N-methyl-N'-nitro-N-nitrosoguanidine-induced transformation and increases chromosomal aberrations.
The morphologic transformation induced in Syrian hamster embryo cells by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) (0.25… 
1979
1979
DNA repair and malignant transformation: effect of X irradiation, 12-O-tetradecanoyl-phorbol-13-acetate, and protease inhibitors on transformation and sister-chromatid exchanges in mouse 10T 1/2…
We have examined the changes which occur in survival and in the frequencies of chromosomal aberrations, sister-chromatid… 
1978
1978
Attack of sea urchin eggs by dogfish phagocytes: model of phagocyte-mediated cellular cytotoxicity.
To test whether lysosomal degranulation of phagocytes is associated with antibody-dependent cytotoxicity, eggs of Arbacia… 
1978
1978
Prevention of normal mouse uterine maturation by antipain and elastatinal: suppression of peroxidase activity.
We had shown previously that the serine protease inhibitors, antipain and leupeptin, restrict uterine DNA snythesis and function… 
1977
1977
Antipain and leupeptin restrict uterine DNA synthesis and function in mice.
As in rats, administration of estradiol to ovariectomized mice results in a trypsin-like proteolytic activity in the uterus… 
Highly Cited
1972
Highly Cited
1972
Structure of antipain, a new Sakaguchi-positive product of streptomyces.
Sir: In the course of our chemical screening of culture filtrates of microorganisms^, a new SAKAGUCHi-positive metabolite was… 
1972
1972
Effect of antipain on lysosomal peptide-hydrolases from swine liver.
In the previous report9) the authors examined the effect of leupeptin, pepstatin and chymostatin on cathepsins A, B and D. In the…