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Aneugens

Known as: Aneuploidy-Inducing Agents, Agents, Aneuploidy-Inducing, Agents, Aneugenic 
Agents which affect CELL DIVISION and the MITOTIC SPINDLE APPARATUS resulting in the loss or gain of whole CHROMOSOMES, thereby inducing an… 
National Institutes of Health

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AneuploidyPolyploidy-Inducing Agentsaspects of radiation effectschemical synthesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
Enhanced sensitivity of peripheral blood lymphocytes from women carrying a BRCA1 mutation towards the mutagenic effects of various cytostatics.
2001
2001
Spindle poisons induce allelic loss in mouse lymphoma cells through mitotic non-disjunction.
1999
1999
A proposal for a simple way to distinguish aneugens from clastogens in the in vitro micronucleus test.
In our previous in vitro micronucleus (MN) study, we showed that aneugens, in addition to inducing micronuclei, induce a higher… 
1998
1998
Use of acridine orange in: flow cytometric assessment of micronuclei induction.
Highly Cited
1997
Highly Cited
1997
A critical evaluation of centromeric labeling to distinguish micronuclei induced by chromosomal loss and breakage in vitro.
Review
1993
Review
1993
The detection and assessment of the aneugenic potential of environmental chemicals: the European Community Aneuploidy Project.
1993
1993
Cytokinesis-block micronucleus assay with kinetochore detection in colchicine-treated human fibroblasts.
Highly Cited
1993
Highly Cited
1993
The use of fluorescence in situ hybridization for the detection of aneugens in cytokinesis-blocked mouse splenocytes.
In the mouse splenocyte assay cytokinesis-blocked micronuclei (MN) and fluorescent in situ hybridization techniques were applied… 
Highly Cited
1989
Highly Cited
1989
Kinetochore detection in micronuclei: an alternative method for measuring chromosome loss.
Whole chromosomes within micronuclei (MN) in cytokinesis-blocked human lymphocytes were detected by using anti-kinetochore… 
1987
1987
A simple and reliable in vitro test system for the analysis of induced aneuploidy as well as other cytogenetic end-points using Chinese hamster cells.
Although aneuploidy is a serious human health problem, the experimental methodology devised until now to study the mechanisms… 
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