Androstenediol

Known as: Hermaphrodiol, 5-Androstene-3beta-17beta-Diol, 5-androstenediol 
An intermediate in TESTOSTERONE biosynthesis, found in the TESTIS or the ADRENAL GLANDS. Androstenediol, derived from DEHYDROEPIANDROSTERONE by the… (More)
National Institutes of Health

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16 relations

Broader (3)

Anabolic AgentsAnabolic steroidsAndrostenediols
Androstenediol/Creatinine:SRto:Pt:Urine:QnAndrostenediol:MRat:24H:Urine:QnAndrostenediol:SCnc:24H:Urine:QnAndrostenediol:SCnc:Pt:Urine:Qn
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HE2100

Papers overview

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Review
2006
Review
2006
Xenobiotic-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons.
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental carcinogens and metabolized by a variety of xenobiotic… (More)
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Highly Cited
2004
Highly Cited
2004
The adrenal androgen androstenediol is present in prostate cancer tissue after androgen deprivation therapy and activates mutated androgen receptor.
Despite an initial response to androgen deprivation therapy, prostate cancer (PCa) progresses eventually from an androgen… (More)
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Review
2003
Review
2003
Glyoxalase I--structure, function and a critical role in the enzymatic defence against glycation.
Glyoxalase I is part of the glyoxalase system present in the cytosol of cells. The glyoxalase system catalyses the conversion of… (More)
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Highly Cited
2002
Highly Cited
2002
Modulation of repair of ultraviolet damage in the host-cell reactivation assay by polymorphic XPC and XPD/ERCC2 genotypes.
DNA repair capacity (DRC) plays an important role in genetic susceptibility to cancer. Polymorphisms of a number of DNA repair… (More)
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Highly Cited
2001
Highly Cited
2001
Relative enzymatic activity, protein stability, and tissue distribution of human steroid-metabolizing UGT2B subfamily members.
Androgens and estrogens play major roles in cell differentiation, cell growth, and peptide secretion in steroid target tissues… (More)
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Highly Cited
2000
Highly Cited
2000
Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and…
The kinetic parameters, steroid substrate specificity and identities of reaction products were determined for four homogeneous… (More)
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Highly Cited
2000
Highly Cited
2000
Repair of tobacco carcinogen-induced DNA adducts and lung cancer risk: a molecular epidemiologic study.
BACKGROUND Only a fraction of cigarette smokers develop lung cancer, suggesting that people differ in their susceptibility to… (More)
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Highly Cited
1996
Highly Cited
1996
Cloning of a novel receptor expressed in rat prostate and ovary.
We have cloned a novel member of the nuclear receptor superfamily. The cDNA of clone 29 was isolated from a rat prostate cDNA… (More)
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Highly Cited
1996
Highly Cited
1996
Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.
Cigarette smoke carcinogens such as benzo[a]pyrene are implicated in the development of lung cancer. The distribution of benzo[a… (More)
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Highly Cited
1974
Highly Cited
1974
Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide
CARCINOGENIC polycyclic hydrocarbons such as the widespread environmental contaminant, benzo(a)pyrene (Fig. 1a), undoubtedly… (More)
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