Androgen-Insensitivity Syndrome

Known as: DHTR DEFICIENCY, Insensitivity Syndrome, Androgen, Resistance Syndrome, Androgen 
A disorder of sexual development transmitted as an X-linked recessive trait. These patients have a karyotype of 46,XY with end-organ resistance to… (More)
National Institutes of Health

Related topics

Related topics

25 relations
AR geneAR wt AlleleAchard-Thiers syndromeEndocrine system
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Broader (5)

Adrenogenital SyndromeDisorders of Sex DevelopmentGenital Diseases, MaleSex Chromosome Aberrations
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Narrower (2)

Reifenstein SyndromeTesticular Feminization

Papers overview

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2018
2018
Androgen Insensitivity Syndrome Androgen Insensitivity Syndrome
Androgen Insensitivity Syndrome (AIS) is a human disorder in which an individual's genetic sex (genotype) differs from that… (More)
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Highly Cited
2006
Highly Cited
2006
Testicular development in the complete androgen insensitivity syndrome.
The complete androgen insensitivity syndrome (CAIS), caused by mutations in the androgen receptor (AR) gene, is associated with… (More)
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Highly Cited
2003
Highly Cited
2003
Psychological outcomes and gender-related development in complete androgen insensitivity syndrome.
We evaluated psychological outcomes and gender development in 22 women with complete androgen insensitivity syndrome (CAIS… (More)
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Highly Cited
2001
Highly Cited
2001
A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy.
The development and growth of prostate cancer depends on the androgen receptor and its high-affinity binding of… (More)
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Highly Cited
2000
Highly Cited
2000
Phenotypic features, androgen receptor binding, and mutational analysis in 278 clinical cases reported as androgen insensitivity syndrome.
Androgen insensitivity syndrome (AIS) is the most common single entity that results in male under-masculinization, but large… (More)
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Highly Cited
2000
Highly Cited
2000
Complete androgen insensitivity syndrome: long-term medical, surgical, and psychosexual outcome.
Controversy concerning the most appropriate treatment guidelines for intersex children currently exists. This is due to a lack of… (More)
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Highly Cited
1998
Highly Cited
1998
Intermolecular NH2-/carboxyl-terminal interactions in androgen receptor dimerization revealed by mutations that cause androgen insensitivity.
Structural alignment of the human androgen receptor dimer was investigated by introducing steroid binding domain mutations that… (More)
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Review
1996
Review
1996
Molecular basis of androgen insensitivity
Androgens are important steroid hormones for expression of the male phenotype. They have characteristic roles during male sexual… (More)
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1992
1992
Testicular feminization: the androgen insensitivity syndrome.
Testicular feminization (TF) is a syndrome due to androgen insensitivity. It occurs in a complete (CTF) and an incomplete (ITF… (More)
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Highly Cited
1989
Highly Cited
1989
Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity.
Androgens act through a receptor protein (AR) to mediate sex differentiation and development of the male phenotype. We have… (More)
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