AR gene

Known as: ANDROGEN RECEPTOR, SMAX1, NR3C4 
This gene plays a role in the transcriptional activation of androgen responsive genes.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Persistent androgen receptor (AR) transcriptional activity underlies resistance to AR-targeted therapy and progression to lethal… (More)
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Highly Cited
2012
Highly Cited
2012
Characterization of the prostate cancer transcriptome and genome has identified chromosomal rearrangements and copy number gains… (More)
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Highly Cited
2012
Highly Cited
2012
The current version of the androgen receptor gene (AR) mutations database is described. A major change to the database is that… (More)
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Highly Cited
2011
Highly Cited
2011
Prostate cancer is characterized by its dependence on androgen receptor (AR) and frequent activation of PI3K signaling. We find… (More)
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Highly Cited
2008
Highly Cited
2008
The standard systemic treatment for prostate cancer (PCa) is androgen ablation, which causes tumor regression by inhibiting… (More)
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Highly Cited
2007
Highly Cited
2007
Androgen deprivation therapy (ADT) remains the primary treatment for advanced prostate cancer. The efficacy of ADT has not been… (More)
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Highly Cited
1997
Highly Cited
1997
Progression of prostate cancer during endocrine therapy is a major clinical problem, the molecular mechanisms of which remain… (More)
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Highly Cited
1995
Highly Cited
1995
Overexpression of amplified genes is often associated with the acquisition of resistance to cancer therapeutic agents in vitro… (More)
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Highly Cited
1994
Highly Cited
1994
Aberrant activation of the androgen receptor (AR) may be one of the mechanisms which contribute to progression of prostatic… (More)
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Highly Cited
1992
Highly Cited
1992
We screened human prostate cancer tissues for the presence of somatic mutations in the hormone binding domain of the androgen… (More)
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