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AR gene

Known as: ANDROGEN RECEPTOR, SMAX1, NR3C4 
This gene plays a role in the transcriptional activation of androgen responsive genes.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
UNLABELLED Despite the impressive clinical activity of the second-generation antiandrogens enzalutamide and ARN-509 in patients… Expand
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Highly Cited
2012
Highly Cited
2012
Characterization of the prostate cancer transcriptome and genome has identified chromosomal rearrangements and copy number gains… Expand
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Highly Cited
2012
Highly Cited
2012
Prostate cancer is the second most common cancer in men worldwide and causes over 250,000 deaths each year. Overtreatment of… Expand
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Highly Cited
2011
Highly Cited
2011
Prostate cancer is characterized by its dependence on androgen receptor (AR) and frequent activation of PI3K signaling. We find… Expand
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Highly Cited
2002
Highly Cited
2002
PURPOSE Ansamycin antibiotics, including 17allylamino-17-demethoxygeldanamycin (17-AAG), inhibit Hsp90 function and cause the… Expand
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Highly Cited
1999
Highly Cited
1999
Spinal bulbar muscular atrophy is a neurodegenerative disorder caused by a polyglutamine expansion in the androgen receptor (AR… Expand
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Highly Cited
1997
Highly Cited
1997
Progression of prostate cancer during endocrine therapy is a major clinical problem, the molecular mechanisms of which remain… Expand
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Highly Cited
1995
Highly Cited
1995
Overexpression of amplified genes is often associated with the acquisition of resistance to cancer therapeutic agents in vitro… Expand
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Highly Cited
1995
Highly Cited
1995
The androgen receptor genotype was determined in the white blood cell DNA of 45 African-American, 39 non-Hispanic white, and 39… Expand
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Highly Cited
1994
Highly Cited
1994
Some transcription factors contain stretches of polyglutamine encoded by repeats of the trinucleotide CAG. Expansion of the CAG… Expand
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