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Alzheimer's Disease
Known as:
Dementia of the Alzheimer's type
, alzheimers dementia
, Senile Dementia, Alzheimer Type
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A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem…
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National Institutes of Health
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Related topics
Related topics
48 relations
24 HR galantamine hydrobromide 8 MG Extended Release Oral Capsule
APOE gene
APOE wt Allele
Basal Nucleus of Meynert
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Narrower (4)
ALZHEIMER DISEASE 2
ALZHEIMER DISEASE 6, LATE-ONSET
Alzheimer Disease 7
Familial Alzheimer Disease (FAD)
Broader (1)
Mental disorders
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
S. Salloway
,
R. Sperling
,
+21 authors
H. Brashear
New England Journal of Medicine
2014
Corpus ID: 11656631
BACKGROUND Bapineuzumab, a humanized anti-amyloid-beta monoclonal antibody, is in clinical development for the treatment of…
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Highly Cited
2014
Highly Cited
2014
Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease.
R. Doody
,
Ronald G. Thomas
,
+10 authors
R. Mohs
New England Journal of Medicine
2014
Corpus ID: 1058222
BACKGROUND Alzheimer's disease is characterized by amyloid-beta plaques, neurofibrillary tangles, gliosis, and neuronal loss…
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Highly Cited
2013
Highly Cited
2013
Molecular Pathology of Alzheimer's Disease
R. Castellani
,
George Perry
2013
Corpus ID: 17042728
Abstract Download Free Sample Alzheimer’s Disease is characterized pathologically by two principal hallmark lesions: the senile…
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Review
2010
Review
2010
Alzheimer's disease: strategies for disease modification
M. Citron
Nature reviews. Drug discovery
2010
Corpus ID: 18987726
Alzheimer's disease is the largest unmet medical need in neurology. Current drugs improve symptoms, but do not have profound…
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Review
2009
Review
2009
Classification and basic pathology of Alzheimer disease
C. Duyckaerts
,
B. Delatour
,
M. Potier
Acta Neuropathologica
2009
Corpus ID: 10661812
The lesions of Alzheimer disease include accumulation of proteins, losses of neurons and synapses, and alterations related to…
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Highly Cited
2006
Highly Cited
2006
Mediterranean diet and risk for Alzheimer's disease
N. Scarmeas
,
Y. Stern
,
M. Tang
,
R. Mayeux
,
J. Luchsinger
Annals of Neurology
2006
Corpus ID: 7698530
Previous research in Alzheimer's disease (AD) has focused on individual dietary components. There is converging evidence that…
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Highly Cited
1996
Highly Cited
1996
Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease
P. Mcgeer
,
M. Schulzer
,
E. Mcgeer
Neurology
1996
Corpus ID: 41141316
Alzheimer's disease (AD) lesions are characterized by the presence of numerous inflammatory proteins.This has led to the…
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Highly Cited
1987
Highly Cited
1987
Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease.
D. Goldgaber
,
M. Lerman
,
O. McBride
,
U. Saffiotti
,
D. C. Gajdusek
Science
1987
Corpus ID: 37848651
Four clones were isolated from an adult human brain complementary DNA library with an oligonucleotide probe corresponding to the…
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Highly Cited
1987
Highly Cited
1987
The genetic defect causing familial Alzheimer's disease maps on chromosome 21.
P. S. George-hyslop
,
R. Tanzi
,
+8 authors
D. Drachman
Science
1987
Corpus ID: 39566104
Alzheimer's disease is a leading cause of morbidity and mortality among the elderly. Several families have been described in…
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Highly Cited
1942
Highly Cited
1942
The mask of sanity.
H. Cleckley
Postgraduate medicine
1942
Corpus ID: 31170939
Psychotic disorders may be concealed behind outer manifestations that give little or no suggestion of anything so serious. The…
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