Alkaline Phosphatase

Known as: Orthophosphoric-monoester phosphohydrolase (alkaline optimum), alkaline phosphatases, glycerophosphatase 
An enzyme that catalyses the cleavage of inorganic phosphate non-specifically from a wide variety of phosphate esters and having a high (greater than… (More)

Topic mentions per year

Topic mentions per year

1938-2017
01000200019382016

Papers overview

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Highly Cited
2007
Highly Cited
2007
Vertebrates harbor abundant lipopolysaccharide (LPS) in their gut microbiota. Alkaline phosphatases can dephosphorylate and… (More)
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Highly Cited
2003
Highly Cited
2003
UNLABELLED Wnt/beta-catenin signaling has recently been suggested to be involved in bone biology. The precise role of this… (More)
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Highly Cited
2003
Highly Cited
2003
Information on the stage of liver fibrosis is essential in managing chronic hepatitis C (CHC) patients. However, most models for… (More)
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Highly Cited
2002
Highly Cited
2002
Osteoblasts mineralize bone matrix by promoting hydroxyapatite crystal formation and growth in the interior of membrane-limited… (More)
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Highly Cited
1988
Highly Cited
1988
This paper describes a novel eukaryotic reporter gene, secreted alkaline phosphatase (SEAP). In transient expression experiments… (More)
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Highly Cited
1986
Highly Cited
1986
A monoclonal antibody to the microtubule-associated protein tau (tau) labeled some neurofibrillary tangles and plaque neurites… (More)
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Highly Cited
1984
Highly Cited
1984
A murine monoclonal antibody specific for calf intestinal alkaline phosphatase has been prepared and used in an unlabeled… (More)
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Highly Cited
1984
Highly Cited
1984
A rapid, sensitive method has been developed to detect antibody-antigen complexes on "Western blots." The methods of H. Towbin, T… (More)
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Highly Cited
1983
Highly Cited
1983
Fluoride is one of the most potent but least well understood stimulators of bone formation in vivo. Bone formation was shown to… (More)
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Highly Cited
1973
Highly Cited
1973
In tumors and embryoid bodies of mouse teratoma a correlation has been established between specific activity of alkaline… (More)
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