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ALPL gene
Known as:
Alkaline Phosphatase, Liver/Bone/Kidney Gene
, TNAP
, ALKALINE PHOSPHATASE, TISSUE-NONSPECIFIC
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This gene may play a role in matrix mineralization.
National Institutes of Health
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Related topics
Related topics
5 relations
ALPL protein, human
Alkaline Phosphatase
Dephosphorylation
Hydrolysis
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Explorer The presence of PHOSPHO 1 in matrix vesicles and its developmental expression prior to skeletal mineralization
Alan J. Stewart
,
S. Roberts
,
E. Seawright
,
Megan G. Davey
,
R. Fleming
,
C. Farquharson
2017
Corpus ID: 727103
PHOSPHO1 is a phosphoethanolamine/phosphocholine phosphatase that has previously been implicated in generating inorganic…
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2017
2017
Improvement of Bone and Dental Phenotype of Murine Hypophosphatasia Mediated by a Single Injection of Lentiviral Gene Therapy
Seiko Yamamoto-Nemoto
,
Kei Ogawa
,
+4 authors
T. Shimizu
2017
Corpus ID: 26428636
Background: Alkaline phosphatase has 4 isozymes, tissue non-specific alkaline phosphatase (TNAP), placental alkaline phosphatase…
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2014
2014
Missense Mutations Responsible for Allows Prediction and Validation of Tissue-nonspecific Alkaline Phosphatase Molecular Evolution of the Molecular Bases of Disease :
J. Silvent
,
B. Gasse
,
E. Mornet
,
J. Sire
2014
Corpus ID: 207783824
2012
2012
Hypophosphatasia: enzyme replacement therapy (ENB-0040) decreases TNSALP substrate accumulation and improves functional outcome in affected adolescents and adults
P. Kishnani
,
C. Rockman-Greenberg
,
+8 authors
H. Landy
2012
Corpus ID: 80467178
2010
2010
HTS identification of compounds activating TNAP at an intermediate concentration of phosphate acceptor detected in luminescent assay
X. Chan
,
Brock T. Brown
,
+10 authors
Ying Su
2010
Corpus ID: 91403474
2010
2010
Table 1, Structure-Activity-Relationships for TNAP Activator Analogues of CID-704205
X. Chan
,
Brock T. Brown
,
+10 authors
Ying Su
2010
Corpus ID: 89556682
2010
2010
Local increased expression of TNAP may contribute to elastic fiber mineralization in PXE
Annovi Giulia
,
B. Federica
,
+6 authors
Quaglino Daniela
2010
Corpus ID: 104327955
Review
2006
Review
2006
A Case of Perinatal Lethal Form of Hypophosphatasia ; and Review of Literatures ACF LAM
Jwy
2006
Corpus ID: 29355326
Received July 3, 2006 Abstract Hypophosphatasia is a rare inborn error of metabolism. The disease is characterised by skeletal…
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2006
2006
Lack of genetic association of the ENPP1 and TNAP genes with chondrocalcinosis
You-Ming Zhang
,
Matthew A. Brown
,
C. Peach
,
G. Russell
,
Paul Wordsworth
2006
Corpus ID: 74749717
2004
2004
Novel Repressor of NF-B-inducing Kinase , Suppresses NF-B Activation *
Wen-Hui Hu
,
Xianming Mo
,
Winston M. Walters
,
R. Brambilla
,
J. Bethea
2004
Corpus ID: 18042697
NFB-inducing kinase (NIK) has been implicated as an essential component of NFB activation. However, the regulatory mechanism of…
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