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Glucagon-like peptide 1 (GLP-1) is a 30-amino acid peptide hormone produced in the intestinal epithelial endocrine L-cells by… Expand Mammals detect temperature with specialized neurons in the peripheral nervous system. Four TRPV-class channels have been… Expand The cellular and molecular mechanisms that enable us to sense cold are not well understood. Insights into this process have come… Expand It has long been assumed that sensory neurons are adapted, through both evolutionary and developmental processes, to the… Expand The sensation of pain alerts us to real or impending injury and triggers appropriate protective responses. Unfortunately, pain… Expand The capsaicin (vanilloid) receptor VR1 is a cation channel expressed by primary sensory neurons of the "pain" pathway… Expand Capsaicin, the main pungent ingredient in ‘hot’ chilli peppers, elicits a sensation of burning pain by selectively activating… Expand The neurotrophins are a small group of dimeric proteins that profoundly affect the development of the nervous system of… Expand The mammalian olfactory system can recognize and discriminate a large number of different odorant molecules. The detection of… Expand Single primary afferent myelinated fibers from cutaneous receptors of cat and monkey were functionally identified by recording… Expand