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Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
In contrast to existing lacZ reporter lines, where lacZ expression cannot easily be detected in living tissue, the EYFP and ECFP reporter strains are useful for monitoring the expression of Cre and tracing the lineage of these cells and their descendants in cultured embryos or organs.
Neuronal specification in the spinal cord: inductive signals and transcriptional codes
- T. Jessell
- BiologyNature reviews genetics
- 1 October 2000
The mechanisms that specify the identity of neural cells have been examined in many regions of the nervous system and reveal a high degree of conservation in the specification of cell fate by key signalling molecules.
A Homeodomain Protein Code Specifies Progenitor Cell Identity and Neuronal Fate in the Ventral Neural Tube
Directed Differentiation of Embryonic Stem Cells into Motor Neurons
Pax6 Controls Progenitor Cell Identity and Neuronal Fate in Response to Graded Shh Signaling
Topographic organization of embryonic motor neurons defined by expression of LIM homeobox genes
Two Critical Periods of Sonic Hedgehog Signaling Required for the Specification of Motor Neuron Identity
Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm
Coordinate Regulation of Motor Neuron Subtype Identity and Pan-Neuronal Properties by the bHLH Repressor Olig2