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Adprt protein, rat

Known as: PARP-1 enzyme, rat, Parp-1 protein, rat, Parp1 protein, rat 
National Institutes of Health

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Poly (ADP-Ribose) Polymerase-1

Papers overview

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Highly Cited
2015
Highly Cited
2015
Quantitative site-specific ADP-ribosylation profiling of DNA-dependent PARPs.
2015
2015
Hyperglycemia accentuates and ketonemia attenuates hypoglycemia-induced neuronal injury in the developing rat brain
Background:Prolonged hypoglycemia leads to brain injury, despite treatment with 10% dextrose. Whether induction of hyperglycemia… 
Highly Cited
2013
Highly Cited
2013
Mapping PARP-1 auto-ADP-ribosylation sites by liquid chromatography-tandem mass spectrometry.
We demonstrate a novel method for the identification of poly(ADP-ribose) polymerase-1 (PARP-1) autopoly(ADP-ribosyl)ation sites… 
2010
2010
Poly(ADP-ribose) Polymerase (PARP)-1-independent Apoptosis-inducing Factor (AIF) Release and Cell Death Are Induced by Eleostearic Acid and Blocked by α-Tocopherol and MEK Inhibition*
Poly(ADP-ribose)polymerase-1 (PARP-1) is thought to be required for apoptosis-inducing factor (AIF) release from mitochondria in… 
Review
2009
Review
2009
Epigenetics: poly(ADP‐ribosyl)ation of PARP‐1 regulates genomic methylation patterns
In the postgenome era, attention is being focused on those epigenetic modifications that modulate chromatin structure to… 
Review
2008
Review
2008
Poly(ADP-ribose)polymerase-1 (PARP-1) in carcinogenesis: potential role of PARP inhibitors in cancer treatment
Poly(ADP-ribose)polymerase-1 (PARP-1) is a nuclear, zinc-finger, deoxyribonucleic acid (DNA)-binding protein that detects… 
Review
2007
Review
2007
Multiple roles for poly(ADP-ribose)polymerase-1 in neurological disease
Highly Cited
2006
Highly Cited
2006
Phthalazinones 2: Optimisation and synthesis of novel potent inhibitors of poly(ADP-ribose)polymerase.
Highly Cited
2006
Highly Cited
2006
Protective effects of the PARP-1 inhibitor PJ34 in hypoxic-reoxygenated cardiomyoblasts
Abstract.To clarify the role of poly(ADP-ribose)polymerase-1 (PARP-1) in myocardial ischemia-reperfusion injury, we explored some… 
Highly Cited
2004
Highly Cited
2004
The discovery and synthesis of novel adenosine substituted 2,3-dihydro-1H-isoindol-1-ones: potent inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1).
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