ALYREF gene

Embryonic stem (ES) cells are pluripotent and of therapeutic potential in regenerative medicine. Understanding pluripotency at… (More)

Apoptosis, or cellular suicide, is important for normal development and tissue homeostasis, but too much or too little apoptosis… (More)

The sequencing of the zebrafish genome should be completed by the end of 2002. Direct assignment of function on the basis of this… (More)

Gene dosage variations occur in many diseases. In cancer, deletions and copy number increases contribute to alterations in the… (More)

The use of individual molecules as functional electronic devices was first proposed in the 1970s (ref. 1). Since then, molecular… (More)

The complement system plays a paradoxical role in the development and expression of autoimmunity in humans. The activation of… (More)

Fusion of viral and cellular membranes by the envelope glyco-protein gp120/gp41 effects entry of HIV-1 into the cell. The… (More)

HIV-1 and related viruses require co-receptors, in addition to CD4, to infect target cells. The chemokine receptor CCR-5 (ref. 1… (More)

THE receptor tyrosine kinase Flk-1 (ref. 1) is believed to play a pivotal role in endothelial development. Expression of the Flk… (More)

AMYOTROPHIC lateral sclerosis (ALS) is a degenerative disorder of motor neurons in the cortex, brainstem and spinal cord1,2. Its… (More)