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ADTN

Known as: 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene, 6,7-ADTN, 6,7-dihydroxy-2-aminotetralin 
National Institutes of Health

Related topics

Related topics

3 relations

Narrower (1)

ADTN hydrobromide

Broader (2)

Dopamine AgonistsTetrahydronaphthalenes

Papers overview

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1984
1984
C(2)-Methylation abolishes DA1 dopamine agonist activity of 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (6,7-ADTN): steric intolerance by the receptor.
The synthesis of 2-amino-2-methyl-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene is reported. This compound did not produce… 
1982
1982
Brain levels and metabolism of the dopaminergic agonist 2-amino-6,7-dihydroxytetrahydronaphthalene after administration of various prodrugs.
The synthesis of four prodrug diesters (diacetyl, diisobutyryl, dipivaloyl, and dibenzoyl) of the potent dopaminergic agonist 2… 
1982
1982
Dopamine stimulates production of cyclic AMP by the salivary gland of the cockroach,Nauphoeta cinerea
Summary1.Dopamine increases cAMP production in the salivary gland ofNauphoeta cinerea.2.This effect is mimicked by 6,7-ADTN and… 
1981
1981
N-Aralkyl substitution of 2-amino-5,6- and -6,7-dihydroxy-1,2,3,4-tetrahydronaphthalenes. 1. Cardiac and pressor/depressor activities.
Amino substitution o rigid forms of dopamine [2-amino-5,6-dihydroxy-1,2,3,4-tetrahydronaphthalene (A-5,6-DTN) and 2-amino-6,7… 
1981
1981
Stereospecific Antagonism by d-Butaclamol of Dopamine‐Induced Relaxation of the Isolated Rabbit Mesenteric Artery
Summary We characterized the properties of vascular dopamine receptors on isolated rabbit mesenteric arteries preincubated with… 
1979
1979
Stereospecific binding of 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene to rat brain dopamine receptors [proceedings].
1979
1979
The use of ADTN (2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene) as a ligand for brain dopamine receptors [proceedings].
were 2.52 + 0.48 and 1.96 + 0.17 nM (n = 5 and the numbers of binding sites were 12.4 + 0.93 and 12.8 + 2.22 pmol/g wet wt (n = 5… 
1978
1978
Effect of the (+)-and (-)-enantiomers of sulpiride on ADTN-induced hyperactivity in the rat [proceedings].
Bilateral injections of the dopamine analogue ADTN (2amino 6,7 -dihydroxy 1,2,3,4 tetrahydronaphtha lene) into the nucleus… 
1978
1978
[3H] 2-Amino-6,7-dihydroxy 1,2,3,4-tetrahydronapthalene (ADTN): a potential specific dopamine receptor ligand.
The characteristics of [3H] 2-amino-6,7-dihydroxy 1,2,3,4-tetrahydronapthalene (ADTN) binding to calf striatal membranes were… 
1977
1977
Conformational requirements for dopamine-induced vasodilation.
The availability of a series of semi-rigid analogs of dopamine and epinine has made it possible to investigate the conformational…