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ACVR2A gene

Known as: ACTRII, ACTIVIN A RECEPTOR, TYPE IIA, ACVR2A 
This gene plays a role in the transforming growth factor-beta signal transduction pathway through constitutive kinase activity.
National Institutes of Health

Related topics

Related topics

8 relations
ACVR2A protein, humanACVR2A wt AlleleActivin A type II receptorLigand Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Inhibition of miR-181a promotes midbrain neuronal growth through a Smad1/5-dependent mechanism: implications for Parkinson’s disease
Abstract Parkinson’s disease (PD) is the second most common neurodegenerative disease, and is characterized by the progressive… 
2014
2014
Temporal regulation of mRNAs for select bone morphogenetic proteins (BMP), BMP receptors and their associated SMAD proteins during bovine early embryonic development: effects of exogenous BMP2 on…
BackgroundWe previously demonstrated embryotrophic actions of maternal (oocyte-derived) follistatin during bovine early… 
2013
2013
Endogenous Protection Derived from Activin A/Smads Transduction Loop Stimulated via Ischemic Injury in PC12 Cells
Activin A (ActA), a member of transforming growth factor-beta (TGF-b) super- family, affects many cellular processes, including… 
Highly Cited
2012
Highly Cited
2012
Nodal signaling regulates the entry into meiosis in fetal germ cells.
The mechanisms regulating the entry into meiosis in mammalian germ cells remain incompletely understood. We investigated the… 
Highly Cited
2006
Highly Cited
2006
High resolution structures of the bone morphogenetic protein type II receptor in two crystal forms: implications for ligand binding.
2005
2005
Zebrafish acvr2a and acvr2b exhibit distinct roles in craniofacial development
To examine the roles of activin type II receptor signaling in craniofacial development, full‐length zebrafish acvr2a and acvr2b… 
1998
1998
Characterization of the extracellular ligand-binding domain of the type II activin receptor.
The binding of a ligand to cell surface receptors initiates a cascade of intracellular signals that generate responses to the… 
1998
1998
Activin Regulates βA-Subunit and Activin Receptor Messenger Ribonucleic Acid and Cellular Proliferation in Activin-Responsive Testicular Tumor Cells.
Activin, a member of the transforming growth factor-beta superfamily of growth and differentiation factors, has a number of… 
1997
1997
Osteoblasts Express Types I and II Activin Receptors During Early Intramembranous and Endochondral Bone Formation
Increasing evidence suggests a potential role for activin in bone formation. However, the cognate receptors through which… 
Highly Cited
1993
Highly Cited
1993
Expression of type II activin receptor genes in the male and female reproductive tissues of the rat.
In addition to the feedback regulation of pituitary FSH secretion, gonadal activins have been shown to modulate physiological… 
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