Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 210,000,593 papers from all fields of science
Search
Sign In
Create Free Account
ACVR2A gene
Known as:
ACTRII
, ACTIVIN A RECEPTOR, TYPE IIA
, ACVR2A
Expand
This gene plays a role in the transforming growth factor-beta signal transduction pathway through constitutive kinase activity.
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
8 relations
ACVR2A protein, human
ACVR2A wt Allele
Activin A type II receptor
Ligand Binding
Expand
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Activin B Induces Noncanonical SMAD1/5/8 Signaling via BMP Type I Receptors in Hepatocytes: Evidence for a Role in Hepcidin Induction by Inflammation in Male Mice.
Susanna Canali
,
A. B. Core
,
+5 authors
Jodie L Babitt
Endocrinology
2016
Corpus ID: 21471609
Induction of the iron regulatory hormone hepcidin contributes to the anemia of inflammation. Bone morphogenetic protein 6 (BMP6…
Expand
Highly Cited
2014
Highly Cited
2014
Treatment of sporadic inclusion body myositis with bimagrumab
A. Amato
,
K. Sivakumar
,
+10 authors
S. Greenberg
Neurology
2014
Corpus ID: 3576611
Objective: To study activin signaling and its blockade in sporadic inclusion body myositis (sIBM) through translational studies…
Expand
Highly Cited
2013
Highly Cited
2013
An Antibody Blocking Activin Type II Receptors Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy
E. Lach‐Trifilieff
,
G. Minetti
,
+9 authors
D. Glass
Molecular and Cellular Biology
2013
Corpus ID: 35966820
ABSTRACT The myostatin/activin type II receptor (ActRII) pathway has been identified to be critical in regulating skeletal muscle…
Expand
Highly Cited
2009
Highly Cited
2009
Biological Functions of miR-29b Contribute to Positive Regulation of Osteoblast Differentiation*
Zhaoyong Li
,
Mohammad Q. Hassan
,
+7 authors
J. Lian
Journal of Biological Chemistry
2009
Corpus ID: 32926972
Bone tissue arises from mesenchymal cells induced into the osteoblast lineage by essential transcription factors and signaling…
Expand
Highly Cited
2008
Highly Cited
2008
Cripto Is a Noncompetitive Activin Antagonist That Forms Analogous Signaling Complexes with Activin and Nodal*
J. Kelber
,
G. Shani
,
E. Booker
,
W. Vale
,
P. Gray
Journal of Biological Chemistry
2008
Corpus ID: 29379794
Cripto plays critical roles during embryogenesis and has been implicated in promoting the growth and spread of tumors. Cripto is…
Expand
Highly Cited
2008
Highly Cited
2008
Bone morphogenetic protein 6 (BMP6) and BMP7 inhibit estrogen-induced proliferation of breast cancer cells by suppressing p38 mitogen-activated protein kinase activation.
M. Takahashi
,
F. Otsuka
,
+6 authors
H. Doihara
Journal of Endocrinology
2008
Corpus ID: 31083169
Estrogen is involved in the development and progression of breast cancer. Here, we investigated the effects of bone morphogenetic…
Expand
Review
2007
Review
2007
A comprehensive expression survey of bone morphogenetic proteins in breast cancer highlights the importance of BMP4 and BMP7
E. Alarmo
,
T. Kuukasjärvi
,
R. Karhu
,
A. Kallioniemi
Breast Cancer Research and Treatment
2007
Corpus ID: 21835168
Bone morphogenetic proteins (BMPs) regulate diverse cellular processes, such as proliferation, differentiation, and apoptosis…
Expand
Highly Cited
2002
Highly Cited
2002
Expression of activin receptors, follistatin and betaglycan by human endometrial stromal cells; consistent with a role for activins during decidualization.
Rebecca L. Jones
,
L. Salamonsen
,
Y. Zhao
,
J. Éthier
,
A. Drummond
,
J. Findlay
Molecular human reproduction
2002
Corpus ID: 17650164
Decidualization of the human endometrium is critical for implantation, but the mechanisms involved are largely unknown. Activin…
Expand
Highly Cited
2000
Highly Cited
2000
Betaglycan binds inhibin and can mediate functional antagonism of activin signalling
K. Lewis
,
P. Gray
,
+4 authors
W. Vale
Nature
2000
Corpus ID: 4393629
Activins and inhibins, structurally related members of the TGF-β superfamily of growth and differentiation factors, are mutually…
Expand
Highly Cited
1994
Highly Cited
1994
Expression of messenger ribonucleic acids encoding the inhibin/activin system during mid- and late-gestation rat embryogenesis.
V. Roberts
,
S. Barth
Endocrinology
1994
Corpus ID: 2371203
We recently demonstrated that inhibin/activin alpha-, beta A-, and beta B-subunit messenger RNAs (mRNAs) are localized in a…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE