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ACVR2A gene

Known as: ACTRII, ACTIVIN A RECEPTOR, TYPE IIA, ACVR2A 
This gene plays a role in the transforming growth factor-beta signal transduction pathway through constitutive kinase activity.
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Induction of the iron regulatory hormone hepcidin contributes to the anemia of inflammation. Bone morphogenetic protein 6 (BMP6… Expand
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Highly Cited
2014
Highly Cited
2014
Objective: To study activin signaling and its blockade in sporadic inclusion body myositis (sIBM) through translational studies… Expand
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Highly Cited
2013
Highly Cited
2013
ABSTRACT The myostatin/activin type II receptor (ActRII) pathway has been identified to be critical in regulating skeletal muscle… Expand
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Highly Cited
2009
Highly Cited
2009
Bone tissue arises from mesenchymal cells induced into the osteoblast lineage by essential transcription factors and signaling… Expand
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Highly Cited
2008
Highly Cited
2008
Estrogen is involved in the development and progression of breast cancer. Here, we investigated the effects of bone morphogenetic… Expand
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Highly Cited
2008
Highly Cited
2008
Cripto plays critical roles during embryogenesis and has been implicated in promoting the growth and spread of tumors. Cripto is… Expand
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Highly Cited
2003
Highly Cited
2003
Activin, nodal, Vg1, and growth and differentiation factor 1 are members of the transforming growth factor β superfamily and… Expand
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Highly Cited
2002
Highly Cited
2002
Decidualization of the human endometrium is critical for implantation, but the mechanisms involved are largely unknown. Activin… Expand
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Highly Cited
2000
Highly Cited
2000
Activins and inhibins, structurally related members of the TGF-β superfamily of growth and differentiation factors, are mutually… Expand
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Highly Cited
1994
Highly Cited
1994
We recently demonstrated that inhibin/activin alpha-, beta A-, and beta B-subunit messenger RNAs (mRNAs) are localized in a… Expand
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