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ACVR2A gene

Known as: ACTRII, ACTIVIN A RECEPTOR, TYPE IIA, ACVR2A 
This gene plays a role in the transforming growth factor-beta signal transduction pathway through constitutive kinase activity.
National Institutes of Health

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8 relations
ACVR2A protein, humanACVR2A wt AlleleActivin A type II receptorLigand Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
BMP2, BMP4, and their receptors are expressed in the differentiating muscle tissues of mouse embryonic tongue
To investigate the role of bone morphogenetic proteins (BMPs) in the differentiation process of skeletal muscle, we analyzed the… 
2005
2005
Zebrafish acvr2a and acvr2b exhibit distinct roles in craniofacial development
To examine the roles of activin type II receptor signaling in craniofacial development, full‐length zebrafish acvr2a and acvr2b… 
2005
2005
An Activin-A/C Chimera Exhibits Activin and Myostatin Antagonistic Properties*
Activins are involved in many physiological and pathological processes and, like other members of the transforming growth factor… 
1999
1999
Activin and inhibin binding to the soluble extracellular domain of activin receptor II.
Activins and inhibins belong to the transforming growth factor-beta-like superfamily of growth and differentiation factors that… 
1999
1999
Mapping of putative binding sites on the ectodomain of the type II TGF‐β receptor by scanning‐deletion mutagenesis and knowledge‐based modeling
1998
1998
Characterization of the extracellular ligand-binding domain of the type II activin receptor.
The binding of a ligand to cell surface receptors initiates a cascade of intracellular signals that generate responses to the… 
1997
1997
Osteoblasts Express Types I and II Activin Receptors During Early Intramembranous and Endochondral Bone Formation
Increasing evidence suggests a potential role for activin in bone formation. However, the cognate receptors through which… 
1995
1995
Molecular characterization of a type I serine-threonine kinase receptor for TGF-beta and activin in the rat pituitary tumor cell line GH3.
GH3 pituitary tumor cells have surface receptors for transforming growth factors-beta (TGF-beta s) and activins/inhibins. GH3… 
1994
1994
Ovarian regulation of pituitary inhibin subunit and activin receptor type II gene expression: evidence for a nonsteroidal inhibitory substance.
Gonadotropin subunit gene expression is regulated by gonadal, hypothalamic, and locally derived hormones. In particular, activin… 
Highly Cited
1993
Highly Cited
1993
Expression of type II activin receptor genes in the male and female reproductive tissues of the rat.
In addition to the feedback regulation of pituitary FSH secretion, gonadal activins have been shown to modulate physiological… 
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