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ACVR2A wt Allele

Known as: ACTRII, ACVR2, Activin A Receptor, Type II wt Allele 
Human ACVR2A wild-type allele is located in the vicinity of 2q22.3 and is approximately 83 kb in length. This allele, which encodes activin receptor… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Objective: To study activin signaling and its blockade in sporadic inclusion body myositis (sIBM) through translational studies… Expand
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Highly Cited
2013
Highly Cited
2013
ABSTRACT The myostatin/activin type II receptor (ActRII) pathway has been identified to be critical in regulating skeletal muscle… Expand
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Highly Cited
2008
Highly Cited
2008
Myostatin is a secreted TGF-beta family member that controls skeletal muscle growth. Humans, cattle, and dogs carrying natural… Expand
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Highly Cited
2000
Highly Cited
2000
Activins and inhibins, structurally related members of the TGF-β superfamily of growth and differentiation factors, are mutually… Expand
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Highly Cited
2000
Highly Cited
2000
Type II activin receptors (ActRII and ActRIIB) are single-transmembrane domain serine/threonine kinase receptors that bind… Expand
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Review
1999
Review
1999
The transforming growth factor β (TGFβ) superfamily of cytokines elicit diverse biological responses by interacting with two… Expand
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Highly Cited
1997
Highly Cited
1997
Activins and inhibins belong to the transforming growth factor beta (TGF-beta)-like superfamily and exert their effects on a… Expand
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Highly Cited
1996
Highly Cited
1996
Activin, a member of the transforming growth factor-beta (TGF beta) cytokine family, acts as a pituitary cell mitogen via a novel… Expand
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Highly Cited
1995
Highly Cited
1995
The β:β activin homodimer and α:β inhibin heterodimer are mutual antagonists which share a common β subunit. Recently, it has… Expand
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Highly Cited
1994
Highly Cited
1994
We have studied the distribution of activin receptor gene expression in the brain, pituitary, ovary, and testis of the adult rat… Expand
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