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ACVR2A protein, human

Known as: ACTRIIA, Activin Receptor Type IIA, ACTR-II 
Activin receptor type-2A (513 aa, ~58 kDa) is encoded by the human ACVR2A gene. This protein is involved in signal transduction and embryonic… Expand
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Background: Activin receptor-like kinase 1 (ALK1) is an important regulator of normal blood vessel formation and pathological… Expand
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Highly Cited
2009
Highly Cited
2009
The effects of ACE-011 on safety, pharmacokinetics, and bone biomarkers were evaluated in healthy, postmenopausal women. Our data… Expand
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Highly Cited
2008
Highly Cited
2008
Hemojuvelin (HJV) is a coreceptor for bone morphogenetic protein (BMP) signaling that regulates hepcidin expression and iron… Expand
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Highly Cited
2008
Highly Cited
2008
Diseases that affect the regulation of bone turnover can lead to skeletal fragility and increased fracture risk. Members of the… Expand
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Highly Cited
2007
Highly Cited
2007
ALK1 is an endothelial-specific type I receptor of the TGFbeta receptor family whose heterozygous mutations cause hereditary… Expand
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Highly Cited
2007
Highly Cited
2007
Vg1, a member of the TGF-beta superfamily of ligands, has been implicated in the induction of mesoderm, formation of primitive… Expand
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Highly Cited
2005
Highly Cited
2005
Bone morphogenetic protein (BMP) ligands signal by binding the BMP type II receptor (BMPR2) or the activin type II receptors… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Two TGFbeta-related proteins, Nodal and Lefty, are implicated in early embryonic patterning of vertebrates. Genetic… Expand
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Highly Cited
2000
Highly Cited
2000
Foregut development produces a characteristic sequence of gastrointestinal and respiratory organs, but the signaling pathways… Expand
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Highly Cited
1998
Highly Cited
1998
Inhibin, activin, and follistatin (FS) are gonadal proteins that appear to have a role in regulating folliculogenesis through… Expand
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