FAQ

ACVR2A protein, human

Known as: ACTRIIA, Activin Receptor Type IIA, ACTR-II 
Activin receptor type-2A (513 aa, ~58 kDa) is encoded by the human ACVR2A gene. This protein is involved in signal transduction and embryonic… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2016
01219982016

Related topics

Related topics

15 relations
ACVR2A geneEnzyme GeneHomo sapiensLigand Binding
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Broader (2)

Activin A type II receptorReceptor Serine/Threonine Kinase

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
ACVR2A protein, human
Plasma membrane
Signal Transduction
Homo sapiens
Phosphotransferases
Protein phosphorylation

Papers overview

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2013
2013
Activins bind and signal via bone morphogenetic protein receptor type II (BMPR2) in immortalized gonadotrope-like cells.
TGFβ superfamily ligands greatly outnumber their receptors. Thus, receptors are shared between ligands and individual ligands can… (More)
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2011
2011
TCam-2 seminoma cell line exhibits characteristic foetal germ cell responses to TGF-beta ligands and retinoic acid.
Germ cell testicular cancer is understood to arise during embryogenesis, based on the persistence of embryonic germ cell markers… (More)
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2009
2009
Activin is a potent growth suppressor of epithelial ovarian cancer cells.
Although activin is a major cytokine produced by the ovary, its role in epithelial ovarian cancer is poorly defined. Here, we… (More)
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2009
2009
Bone morphogenetic protein-7 induces telomerase inhibition, telomere shortening, breast cancer cell senescence, and death via Smad3.
Human telomerase reverse transcriptase (hTERT) is central to maintain telomeres for continuous cell proliferation, but it remains… (More)
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2004
2004
Activin type II receptor restoration in ACVR2-deficient colon cancer cells induces transforming growth factor-beta response pathway genes.
The activin type II receptor (ACVR2) gene is a putative tumor suppressor gene that is frequently mutated in microsatellite… (More)
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2004
2004
Activin Type II Receptor Restoration in ACVR2-Deficient Colon Cancer Cells Induces Transforming Growth Factor- Response Pathway Genes
The activin type II receptor (ACVR2) gene is a putative tumor suppressor gene that is frequently mutated in microsatellite… (More)
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2004
2004
Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the villous tissue of miscarriage patients.
Maternal circulating levels of inhibin A are significantly lower in patients with clinical symptoms of miscarriage. The objective… (More)
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2003
2003
Inhibin, activin, follistatin, activin receptors and beta-glycan gene expression in the placental tissue of patients with pre-eclampsia.
The objective of this study was to quantify the relative expression of inhibin alpha, inhibin/activin beta(A), beta(B), beta(C… (More)
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2003
2003
Normal reproductive function in InhBP/p120-deficient mice.
The inhibins are gonadal transforming growth factor beta superfamily protein hormones that suppress pituitary follicle… (More)
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1998
1998
Activin regulates betaA-subunit and activin receptor messenger ribonucleic acid and cellular proliferation in activin-responsive testicular tumor cells.
Activin, a member of the transforming growth factor-beta superfamily of growth and differentiation factors, has a number of… (More)
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