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ABCC8 gene

Known as: SUR1, HI, ABC36 
 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Aims/hypothesisGlucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone with anti-apoptotic effects on the… Expand
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE—The purpose of this study was to investigate whether genetic variants could influence the antidiabetic efficacy of… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The ATP-sensitive potassium (K(ATP)) channel, composed of the beta-cell proteins sulfonylurea receptor (SUR1) and… Expand
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Highly Cited
2003
Highly Cited
2003
The genes ABCC8 and KCNJ11, which encode the subunits sulfonylurea receptor 1 (SUR1) and inwardly rectifying potassium channel… Expand
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Review
2002
Review
2002
Sulfonylureas are widely used to treat type 2 diabetes because they stimulate insulin secretion from pancreatic beta-cells. They… Expand
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Review
1999
Review
1999
KATP channels are a newly defined class of potassium channels based on the physical association of an ABC protein, the… Expand
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Highly Cited
1996
Highly Cited
1996
We have isolated a cDNA encoding a novel isoform of the sulfonylurea receptor from a mouse heart cDNA library. Coexpression of… Expand
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Highly Cited
1996
Highly Cited
1996
Closure of ATP-sensitive potassium channels in pancreatic islet beta-cells initiates a cascade of events that leads to insulin… Expand
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Highly Cited
1995
Highly Cited
1995
Sulfonylureas are a class of drugs widely used to promote insulin secretion in the treatment of non-insulin-dependent diabetes… Expand
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Highly Cited
1995
Highly Cited
1995
Familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated… Expand
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