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A-317491

Known as: A317491 
National Institutes of Health

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2 relations

Broader (2)

PhenolsPolycyclic Compounds

Papers overview

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2019
2019
Activation of Prejunctional P2x2/3 Heterotrimers by ATP Enhances the Cholinergic Tone in Obstructed Human Urinary Bladders
The objective of this study was to investigate the role of ATP in cholinergic neurotransmission in the urinary bladder of control… 
2018
2018
The Molecular Determinants of Small-Molecule Ligand Binding at P2X Receptors
P2X receptors are trimeric eukaryotic ATP-gated cation channels. Extracellular ATP—their physiological ligand—is released as a… 
2011
2011
P2 receptor antagonists prevent synaptic failure and extracellular signal‐regulated kinase1/2 activation induced by oxygen and glucose deprivation in rat CA1 hippocampus in vitro
To investigate the role of purinergic P2 receptors under ischemia, we studied the effect of P2 receptor antagonists on synaptic… 
2011
2011
Identification of P2X₃ and P2X₇ purinergic receptors activated by ATP in rat lacrimal gland.
PURPOSE. To identify the type of purinergic receptors activated by adenosine triphosphate (ATP) in rat lacrimal gland and to… 
2010
2010
Role of midbrain periaqueductal gray P2X3 receptors in electroacupuncture-mediated endogenous pain modulatory systems
2010
2010
Loss of muscarinic and purinergic receptors in urinary bladder of rats with hydrochloric acid-induced cystitis.
Highly Cited
2008
Highly Cited
2008
Therapeutic effects of the putative P2X3/P2X2/3 antagonist A-317491 on cyclophosphamide-induced cystitis in rats
It is suggested that ATP and purinergic P2X receptors are involved in overactive bladder. In this study, we investigated the… 
2008
2008
Role of P2X3 receptor in myocardial ischemia injury and nociceptive sensory transmission
2007
2007
Purinergic P2X receptor activation induces emetic responses in ferrets and Suncus murinus (house musk shrews)
Despite the rapid progress made in understanding the significant role played by signalling via extracellular ATP in physiology… 
Review
2005
Review
2005
Antinociceptive properties of a non-nucleotide P2X3/P2X2/3 receptor antagonist.
Acute systemic administration of a novel and highly selective non-nucleotide P2X(3)/P2X(2/3) receptor antagonist, A-317491, has… 
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