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8-aminoguanosine

National Institutes of Health

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Broader (3)

Enzyme InhibitorsGuanosineImmunosuppressive Agents
analogs & derivatives

Papers overview

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2017
2017
Correction to “8-Aminoguanosine and 8-Aminoguanine Exert Diuretic, Natriuretic, Glucosuric, and Antihypertensive Activity”
In the above article [Jackson EK, Gillespie DG, and Zaichuan Mi (2016) J Pharmacol Exp Ther 359(3):420–435. DOI: https://doi.org… 
2002
2002
’ Synthesis of Guanine and Formycin B Derivatives as Potential Inhibitors of Purine Nucleoside Phosphorylase
In an effort to develop potent human purine nucleoside phosphorylase (PNP) inhibitors as immunosuppressive and chemotherapeutic… 
1986
1986
Effects of 8-aminoguanosine and 2'-deoxyguanosine on the human mixed lymphocyte reaction (MLR). I. Description of the inhibition
Patients deficient in purine nucleoside phosphorylase (PNP) generally have a pronounced deficiency in T cell function with no… 
1985
1985
Histological and immunological evaluation of gnotobiotic C3H/He mice following i.v. administration of 8-aminoguanosine and 2'deoxyguanosine.
1983
1983
The metabolism of deoxyguanosine and guanosine in human B and T lymphoblasts. A role for deoxyguanosine kinase activity in the selective T-cell defect associated with purine nucleoside phosphorylase…
Purine nucleoside phosphorylase (NP; EC 2.4.2.1) deficiency is associated with defective T-cell and normal B-cell immunity…