7-Alkoxycoumarin O-Dealkylase

Known as: O-Deethylase, 7-Ethoxycoumarin, 7 Ethoxycoumarin Dealkylase, Ethoxycoumarin O Deethylase 
A drug-metabolizing enzyme found in the hepatic, placental and intestinal microsomes that metabolizes 7-alkoxycoumarin to 7-hydroxycoumarin. The… (More)
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
The aim of this study was to characterise biomarker responses in three-spined sticklebacks exposed to copper. For this purpose… (More)
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Highly Cited
2004
Highly Cited
2004
The measurement of the effect of new chemical entities on human cytochrome P450 marker activities using in vitro experimentation… (More)
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Highly Cited
2004
Highly Cited
2004
DE-71, a commercial mixture, was used to test the sensitivity of the female and male pubertal protocol to detect thyroid active… (More)
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Highly Cited
2002
Highly Cited
2002
The objective of the current study was to characterize the effects of DE-71 (a commercial polybrominated diphenyl ether mixture… (More)
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Highly Cited
2002
Highly Cited
2002
A prolonged toxicity study was carried out in young European eel (Anguilla anguilla L.) to evaluate the effects of environmental… (More)
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Highly Cited
2001
Highly Cited
2001
Polybrominated diphenyl ethers (PBDEs), used as flame retardants, are ubiquitous environmental contaminants. PBDEs act as… (More)
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Highly Cited
1993
Highly Cited
1993
Cytokines are thought to cause the depression of cytochrome P-450 (CYP)-associated drug metabolism in humans during inflammation… (More)
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1989
1989
The effects of six inducers and malotilate on 7-alkoxycoumarin O-dealkylase activities in rat liver microsomes were examined… (More)
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1983
1983
The in vitro biotransformation of 7-alkoxycoumarin by rat liver microsomes was studied to develop a simple and accurate assay… (More)
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1982
1982
The in vitro metabolic fate of 7-alkoxycoumarin was studied using liver microsomes. Microsomal enzyme catalyzed dealkylation of 7… (More)
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