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7-Alkoxycoumarin O-Dealkylase

Known as: O-Deethylase, 7-Ethoxycoumarin, 7 Ethoxycoumarin Dealkylase, Ethoxycoumarin O Deethylase 
A drug-metabolizing enzyme found in the hepatic, placental and intestinal microsomes that metabolizes 7-alkoxycoumarin to 7-hydroxycoumarin. The… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The main objective of the present study was to investigate possible links between biomarkers and swimming performance in the… Expand
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Highly Cited
2004
Highly Cited
2004
  • R. Walsky, R. Obach
  • Drug metabolism and disposition: the biological…
  • 2004
  • Corpus ID: 8789343
The measurement of the effect of new chemical entities on human cytochrome P450 marker activities using in vitro experimentation… Expand
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Highly Cited
2004
Highly Cited
2004
DE-71, a commercial mixture, was used to test the sensitivity of the female and male pubertal protocol to detect thyroid active… Expand
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Highly Cited
2002
Highly Cited
2002
The objective of the current study was to characterize the effects of DE-71 (a commercial polybrominated diphenyl ether mixture… Expand
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Highly Cited
2002
Highly Cited
2002
A prolonged toxicity study was carried out in young European eel (Anguilla anguilla L.) to evaluate the effects of environmental… Expand
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Highly Cited
2001
Highly Cited
2001
Polybrominated diphenyl ethers (PBDEs), used as flame retardants, are ubiquitous environmental contaminants. PBDEs act as… Expand
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Highly Cited
2000
Highly Cited
2000
In order to perform environmental risk assessments with regard to oil contamination in the sea, it is important to obtain… Expand
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Highly Cited
1997
Highly Cited
1997
Heme metabolism normally involves enzymatic conversion to biliverdin and subsequently to bilirubin, catalyzed by heme oxygenase… Expand
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Highly Cited
1993
Highly Cited
1993
Cytokines are thought to cause the depression of cytochrome P-450 (CYP)-associated drug metabolism in humans during inflammation… Expand
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Highly Cited
1978
Highly Cited
1978
An improved in vitro fluorometric assay of the O-deethylation of 7-ethoxycoumarin which is at least 10 times more sensitive than… Expand
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