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6-nitrochrysene

Known as: 6-NC 
A synthetic solid appearing as chrome-red crystals or orange-yellow to light-yellow needles that is slightly soluble in acetic acid, cold ethanol… 
National Institutes of Health

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1 relation

Broader (1)

Chrysenes

Papers overview

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2001
2001
Determination of nitroarenes in precipitation collected in Kanazawa, Japan.
Highly Cited
1999
Highly Cited
1999
Polycyclic nitroarenes (nitro-PAHs) as biomarkers of exposure to diesel exhaust.
1993
1993
Roles of human hepatic and pulmonary cytochrome P450 enzymes in the metabolism of the environmental carcinogen 6-nitrochrysene.
6-Nitrochrysene is remarkably tumorigenic in the lung and liver of newborn mice and approximates the activities of certain… 
1989
1989
Comparative lung tumorigenicity of parent and mononitro-polynuclear aromatic hydrocarbons in the BLU:Ha newborn mouse assay.
1989
1989
Comparative tumorigenicity of 6-nitrochrysene and its metabolites in newborn mice.
The tumorigenic activities of 6-nitrochrysene and its metabolites were evaluated in the newborn mouse model. Groups of mice were… 
1989
1989
Mutagenicity, metabolism and DNA adduct formation of 6-nitrochrysene in Salmonella typhimurium.
The mutagenic activities of 6-nitrochrysene (6-NC) and its previously identified metabolites were evaluated in Salmonella… 
1988
1988
Metabolism of 6-nitrochrysene by intestinal microflora
Since bacterial nitroreduction may play a critical role in the activation of nitropolycyclic aromatic hydrocarbons, we have used… 
1987
1987
Identification of C8-modified deoxyinosine and N2- and C8-modified deoxyguanosine as major products of the in vitro reaction of N-hydroxy-6-aminochrysene with DNA and the formation of these adducts…
Since 6-nitrochrysene and 6-aminochrysene have shown activity in carcinogenicity bioassays, we have begun an investigation of… 
1985
1985
6-Nitrochrysene is a potent tumorigen in newborn mice.
A newborn mouse (BLU:Ha) lung adenoma bioassay demonstrated that 6-nitrochrysene was a highly potent tumorigen. It induced 100… 
1984
1984
Identification of trans-1,2-dihydro-1,2-dihydroxy-6-nitrochrysene as a major mutagenic metabolite of 6-nitrochrysene.
Liver 9000 X g supernatant from rats was used to study the metabolism of [6- 14C]nitrochrysene under aerobic conditions. The… 
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