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5-ethynyl-1-ribofuranosylimidazole-4-carboxamide

Known as: 5-ERFIC, EICAR 
National Institutes of Health

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1 relation

Broader (1)

Ribonucleosides

Papers overview

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2017
2017
Evaluation of cell viability dyes in antiviral assays with RNA viruses that exhibit different cytopathogenic properties.
2010
2010
Antiviral efficacy of EICAR against canine distemper virus (CDV) in vitro.
Review
1999
Review
1999
Role of antimetabolites of purine and pyrimidine nucleotide metabolism in tumor cell differentiation.
1999
1999
Mechanism-based design of inosine 5-monophosphate dehydrogenase inhibitors: synthesis and biological activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide (EICAR) and its derivatives.
Inosine 5 -monophosphate dehydrogenase (IMPDH) catalyzes the nicotinamide adenine dinucleotide (NAD)-dependent oxidation of… 
1996
1996
Inactivation of inosine 5'-monophosphate dehydrogenase by the antiviral agent 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide 5'-monophosphate.
Inosine 5'-monophosphate dehydrogenase (IMPDH) is the rate-limiting enzyme in de novo guanine nucleotide biosynthesis. IMPDH… 
1996
1996
Inhibitors of infectious pancreatic necrosis virus (IPNV) replication.
Highly Cited
1993
Highly Cited
1993
Eicar (5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide). A novel potent inhibitor of inosinate dehydrogenase activity and guanylate biosynthesis.
Highly Cited
1992
Highly Cited
1992
Antiviral activities of ribavirin, 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide, and 6'-(R)-6'-C-methylneplanocin A against several ortho- and paramyxoviruses
5-Ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide (EICAR) and 6'-(R)-6'-C-methylneplanocin A (TJ13025) are two novel… 
Highly Cited
1991
Highly Cited
1991
Antiviral activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4- carboxamide and related compounds
A series of novel compounds, 5-alkynyl-1-beta-D-ribofuranosylimidazole-4- carboxamides, have been identified as broad-spectrum… 
1991
1991
Nucleosides and nucleotides. 96. Synthesis and antitumor activity of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide (EICAR) and its derivatives.
The palladium-catalyzed cross-coupling reaction of 5-iodo-1-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)imidazole-4- carboxamide (8… 
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