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5' Untranslated Regions

Known as: Leader mRNA Sequences, 5'UTR, mRNA Leader Sequences 
Sequences on the 5' end of messenger RNAs that are not translated into protein. 5'UTR extends from the transcription start site to just before the… 
National Institutes of Health

Related topics

Related topics

4 relations
5' Flanking RegionChromosomesaspects of radiation effectsphysiological aspects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5′ UTR as in the 3′ UTR
In animals, microRNAs (miRNAs) bind to the 3′ UTRs of their target mRNAs and interfere with translation, although the exact… 
Highly Cited
2007
Highly Cited
2007
An RNA G-quadruplex in the 5' UTR of the NRAS proto-oncogene modulates translation.
Guanine-rich nucleic acid sequences can adopt noncanonical four-stranded secondary structures called guanine (G)-quadruplexes… 
Review
2006
Review
2006
A high-resolution map of transcription in the yeast genome.
There is abundant transcription from eukaryotic genomes unaccounted for by protein coding genes. A high-resolution genome-wide… 
Highly Cited
2000
Highly Cited
2000
Identification of polymorphisms within the vascular endothelial growth factor (VEGF) gene: correlation with variation in VEGF protein production.
Dysregulated vascular endothelial growth factor (VEGF) expression has been implicated as a major contributor to the development… 
Highly Cited
1998
Highly Cited
1998
Double-stranded RNA induces mRNA degradation in Trypanosoma brucei.
Double-stranded RNA (dsRNA) recently has been shown to give rise to genetic interference in Caenorhabditis elegans and also is… 
Review
1991
Review
1991
Properties of the novel proinflammatory supergene "intercrine" cytokine family.
A family consisting of at least ten distinct novel 8-10 kd cytokines has been identified over the past 12 years. These cytokines… 
Highly Cited
1988
Highly Cited
1988
Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation.
The biosynthetic rates for both the transferrin receptor (TfR) and ferritin are regulated by iron. An iron-responsive element… 
Highly Cited
1987
Highly Cited
1987
A human beta-actin expression vector system directs high-level accumulation of antisense transcripts.
We have constructed a mammalian expression vector consisting of 3 kilobases of the human beta-actin gene 5' flanking sequence… 
Highly Cited
1983
Highly Cited
1983
Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently…
cDNA clones encoding three classes of human actins have been isolated and characterized. The first two classes (gamma and beta… 
Highly Cited
1983
Highly Cited
1983
Isolation, sequence analysis, and intron-exon arrangement of the gene encoding bovine rhodopsin
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