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3-hydroxyquinidine

Known as: 3-hydroxyquinine, 6'-methoxycinchonan-3,9-diol 
 
National Institutes of Health

Papers overview

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2010
2010
AIMS To evaluate the pharmacokinetic interactions between ritonavir and quinine in healthy volunteers. METHODS Ten healthy… Expand
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2007
2007
Summary:  Purpose: Carbamazepine (CBZ) and oxcarbazepine (OXCZ) are well‐known inducers of drug metabolism via CYP3A4. Indirect… Expand
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2003
2003
A simple high-performance liquid chromatographic method for the simultaneous analysis of quinine and 3-hydroxyquinine in blood… Expand
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Highly Cited
2000
Highly Cited
2000
Prolongation of the electrocardiographic QT interval by drugs is associated with the occurrence of a potentially lethal form of… Expand
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1999
1999
To investigate the roles of CYP3A4 and CYP1A2 in the 3‐hydroxylation of quinine in vivo. 
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Highly Cited
1997
Highly Cited
1997
AIMS Our previous studies using in vitro hepatic microsomal preparations suggested that the hepatic metabolism of quinine to form… Expand
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Highly Cited
1997
Highly Cited
1997
AbstractObjective: To assess the factors that contribute to impaired quinine clearance in acute falciparum malaria. Patients… Expand
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Highly Cited
1997
Highly Cited
1997
Quinidine is eliminated mainly by CYP3A4‐mediated metabolism. Itraconazole interacts with some but not all of the substrates of… Expand
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Highly Cited
1996
Highly Cited
1996
Studies using human liver microsomes and nine recombinant human cytochrome P450 (CYP) isoforms (CYP1A1, 1A2, 2A6, 2B6, 2C9, 2C19… Expand
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1995
1995
Our previous studies have shown that cigarette smoking and rifampicin pretreatment enhance the elimination of quinine, metabolism… Expand
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