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3-hydroxyquinidine

Known as: 3-hydroxyquinine, 6'-methoxycinchonan-3,9-diol 
National Institutes of Health

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2 relations

Broader (1)

Quinidine
analogs & derivatives

Papers overview

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2004
2004
Pharmacokinetics and metabolism of quinidine in extensive and poor metabolisers of sparteine
SummaryThe pharmacokinetics and metabolism of quinidine were investigated in extensive and poor metabolisers of sparteine. No… 
1998
1998
MUTUAL INHIBITION BETWEEN QUININE AND ETOPOSIDE BY HUMAN LIVER MICROSOMES Evidence for Cytochrome P 4503 A 4 Involvement in Their Major Metabolic
  • 1998
  • Corpus ID: 9230584
The mutual inhibition between quinine and etoposide with their major metabolic pathways (i.e. quinine 3-hydroxylation and… 
1985
1985
Elimination kinetic of high polar metabolites pool of quinidine from human serum.
The elimination half-life of high polar metabolites pool of quinidine (t1/2 beta = 6.1 h) has been determined in a quinidine… 
1984
1984
[Quinidine and enzyme induction. Erroneous interpretation of the plasma levels of 3-hydroxyquinidine and O-demethylquinidine].
1983
1983
Demi-vie d'élimination de la 3-hydroxyquinidine chez l'homme.
1983
1983
[Elimination half-life of 3-hydroxyquinidine in man].
1983
1983
[Comparison of the cardiac electrophysiologic effects of quinidine, 3-hydroxyquinidine and 3-hydroxyhydroquinidine in the anesthesized dog. Study of plasma dose response relations].
1982
1982
An HPLC method for the quantitation of quinidine and its metabolites in plasma: an application to a quinidine-phenytoin drug interaction study.
A rapid and simple method is described for the separation of quinidine (Q), its metabolites 3-hydroxyquinidine (30HQ) and 2… 
1982
1982
Disposition of quinidine in the rabbit.
Quinidine shows two-compartment characteristics in rabbits with a terminal half-life of 67 min for total drug and 58 min for… 
1982
1982
[Chronic renal insufficiency. Elevated levels of the active metabolite (3-hydroxyquinidine) of quinidine].