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3-hydroxyquinidine

Known as: 3-hydroxyquinine, 6'-methoxycinchonan-3,9-diol 
National Institutes of Health

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Broader (1)

Quinidine
analogs & derivatives

Papers overview

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2008
2008
Quinine clearance during continuous veno-venous high-volume hemofiltration
Quinine is eliminated primarily via hepatic biotransformation and only 15–30% is urinary excreted. There is no standard… 
2004
2004
Pharmacokinetics and metabolism of quinidine in extensive and poor metabolisers of sparteine
SummaryThe pharmacokinetics and metabolism of quinidine were investigated in extensive and poor metabolisers of sparteine. No… 
1998
1998
MUTUAL INHIBITION BETWEEN QUININE AND ETOPOSIDE BY HUMAN LIVER MICROSOMES Evidence for Cytochrome P 4503 A 4 Involvement in Their Major Metabolic
  • 1998
  • Corpus ID: 9230584
The mutual inhibition between quinine and etoposide with their major metabolic pathways (i.e. quinine 3-hydroxylation and… 
1985
1985
Elimination kinetic of high polar metabolites pool of quinidine from human serum.
The elimination half-life of high polar metabolites pool of quinidine (t1/2 beta = 6.1 h) has been determined in a quinidine… 
1983
1983
Demi-vie d'élimination de la 3-hydroxyquinidine chez l'homme.
1983
1983
[Elimination half-life of 3-hydroxyquinidine in man].
1982
1982
An HPLC method for the quantitation of quinidine and its metabolites in plasma: an application to a quinidine-phenytoin drug interaction study.
A rapid and simple method is described for the separation of quinidine (Q), its metabolites 3-hydroxyquinidine (30HQ) and 2… 
1982
1982
Disposition of quinidine in the rabbit.
Quinidine shows two-compartment characteristics in rabbits with a terminal half-life of 67 min for total drug and 58 min for… 
1982
1982
Improved liquid-chromatographic assay of quinidine and its metabolites in biological fluids.
We describe a simple, rapid, and specific assay for quinidine and its known metabolites in plasma, urine, and bile. Plasma… 
1982
1982
[Chronic renal insufficiency. Elevated levels of the active metabolite (3-hydroxyquinidine) of quinidine].
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