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Quinidine

Known as: (S)-(6-Methoxyquinolin-4-yl)((2R,5R)-5-vinylquinuclidin-2-yl)methanol, Chinidinum, Cinchonan-9-ol, 6'-methoxy-, (9S)- 
An alkaloid extracted from the bark of the Cinchona tree with class 1A antiarrhythmic and antimalarial effects. Quinidine stabilizes the neuronal… Expand
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
Paroxetine, a selective serotonin reuptake inhibitor, is a potent inhibitor of cytochrome P450 2D6 (CYP2D6) activity, but the… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Although quinidine is known to elevate plasma digoxin concentrations, the mechanism underlying this interaction is not… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The Brugada syndrome is characterized by marked ST-segment elevation in the right precordial ECG leads and is… Expand
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Review
1996
Review
1996
Clinical trials are the standard scientific method for evaluating a new biological agent, drug, device, or procedure for the… Expand
Review
1990
Review
1990
Because individual studies evaluating the role of quinidine in the maintenance of sinus rhythm after cardioversion from chronic… Expand
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Review
1986
Review
1986
Quinidine therapy is one of the most common causes of the acquired long QT syndrome and torsade de pointes. In reviewing clinical… Expand
Review
1976
Review
1976
A case is described of presumed quinidine hepatotoxicity, characterized by the development of fever, abnormal serum transaminase… Expand
Review
1964
Review
1964
QUINIDINE occupies an almost unique place in the therapy of cardiac arrhythmias. In the 45-odd years of its clinical use only… Expand
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Highly Cited
1964
Highly Cited
1964
Effects of stimulation of the cardiac sympathetic nerves and intravenous administration of sympathomimetic amines on the multiple… Expand
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Highly Cited
1957
Highly Cited
1957
Abstract Four cases of deaf-mutism combined with a peculiar heart disease have been observed in one family. The parents and 2… Expand