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Quinidine

Known as: (S)-(6-Methoxyquinolin-4-yl)((2R,5R)-5-vinylquinuclidin-2-yl)methanol, Chinidinum, Cinchonan-9-ol, 6'-methoxy-, (9S)- 
An alkaloid extracted from the bark of the Cinchona tree with class 1A antiarrhythmic and antimalarial effects. Quinidine stabilizes the neuronal… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
To evaluate dextromethorphan combined with ultra low‐dose quinidine (DMq) for treating pseudobulbar affect (PBA) in patients with… Expand
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Highly Cited
2007
Highly Cited
2007
Background— Cardiac ion channelopathies are responsible for an ever-increasing number and diversity of familial cardiac… Expand
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Highly Cited
2006
Highly Cited
2006
To evaluate the efficacy and safety of DM/Q (capsules containing dextromethorphan [DM] and quinidine [Q]) compared with placebo… Expand
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Highly Cited
2003
Highly Cited
2003
Paroxetine, a selective serotonin reuptake inhibitor, is a potent inhibitor of cytochrome P450 2D6 (CYP2D6) activity, but the… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND Tamoxifen, a selective estrogen receptor modulator (SERM), is converted to 4-hydroxy-tamoxifen and other active… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The Brugada syndrome is characterized by marked ST-segment elevation in the right precordial ECG leads and is… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Although quinidine is known to elevate plasma digoxin concentrations, the mechanism underlying this interaction is not… Expand
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Highly Cited
1998
Highly Cited
1998
IN 1948, BERNARD AND SOULIER described a young male patient with a severe bleeding disorder that was characterized by a prolonged… Expand
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Highly Cited
1993
Highly Cited
1993
OBJECTIVES AND METHODS To gain insight into possible mechanisms of and predisposing factors for torsades de pointes during… Expand
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Highly Cited
1957
Highly Cited
1957
Abstract Four cases of deaf-mutism combined with a peculiar heart disease have been observed in one family. The parents and 2… Expand
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