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Quinidine

Known as: (S)-(6-Methoxyquinolin-4-yl)((2R,5R)-5-vinylquinuclidin-2-yl)methanol, Chinidinum, Cinchonan-9-ol, 6'-methoxy-, (9S)- 
An alkaloid extracted from the bark of the Cinchona tree with class 1A antiarrhythmic and antimalarial effects. Quinidine stabilizes the neuronal… 
National Institutes of Health

Related topics

Related topics

44 relations

Narrower (13)

10,11-dihydroxydihydroquinidine N-oxide2'-oxoquinidinone3-hydroxyhydroquinidine3-hydroxyquinidine
12 HR Propafenone Hydrochloride 225 MG Extended Release Oral CapsuleAmprenavirAtrial FibrillationCisapride

Broader (7)

Adrenergic alpha-AntagonistsAlkaloidsAnti-Arrhythmia AgentsAntimalarials

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1994
1994
Functional studies of P-glycoprotein in inside-out plasma membrane vesicles derived from murine erythroleukemia cells overexpressing MDR 3.
Scott R. Schlemrner and Francis M. Sirotnak Page 31061: The legend to Fig. 1 should read “Northern blot of mRNA from MEL/VCR-6… 
Highly Cited
1986
Highly Cited
1986
Sparteine oxidation is practically abolished in quinidine-treated patients.
In eight patients a sparteine-test was carried out immediately before and after 1 week of treatment with quinidine 600-800 mg day… 
1982
1982
The digoxin-quinidine interaction.
quinidine (an incidence of 93%). Sixteen patients developed gastrointestinal side effects of nausea, anorexia, or vomiting (an… 
Highly Cited
1980
Highly Cited
1980
Effects of quinidine on serum digoxin concentration: a prospective study.
Results of studies of 15 adults placed on quinidine therapy after their serum digoxin concentrations were stabilized showed… 
Highly Cited
1977
Highly Cited
1977
Specific determination of quinidine and (3S)-3-hydroxyquinidine in human serum by high-pressure liquid chromatography.
: A sensitive and selective HPLC assay was developed to measure quinidine and (3S)-3-hydroxyquinidine in the serum of patients… 
1973
1973
Examination of quinidine and quinine and their pharmaceutical preparations.
Methods for the detection and measurement of possible contaminants in quinidine and quinine and their pharmaceutical preparations… 
1958
1958
Successful treatment of quinidine and procaine amide intoxication; report of three cases.
EARLIER observations from this laboratory demonstrated in the laboratory animal the efficacy of molar sodium lactate in reversing… 
Highly Cited
1957
Highly Cited
1957
A possible mechanism of action of quinidine.
Quinidine increases the refractory period and depresses both the rate and amplitude of beat of isolated rabbit atria. These… 
Highly Cited
1953
Highly Cited
1953
The mechanism of quinidine purpura.
A case of thrombocytopenic purpura was studied and evidence of a specific hypersensitivity mechanism was found. The following… 
1953
1953
Observations on Cases of Thrombocytopenic Purpura Due to Quinine, Sulphamezathine, and Quinidine
(RECEIVED FOR PUBLICATIONMARCH 26,1953) Toxicpurpura occurringin personswhohave previously beensensitized bydrug-taking often… 
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