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Quinidine

Known as: (S)-(6-Methoxyquinolin-4-yl)((2R,5R)-5-vinylquinuclidin-2-yl)methanol, Chinidinum, Cinchonan-9-ol, 6'-methoxy-, (9S)- 
An alkaloid extracted from the bark of the Cinchona tree with class 1A antiarrhythmic and antimalarial effects. Quinidine stabilizes the neuronal… 
National Institutes of Health

Related topics

Related topics

44 relations

Narrower (13)

10,11-dihydroxydihydroquinidine N-oxide2'-oxoquinidinone3-hydroxyhydroquinidine3-hydroxyquinidine
12 HR Propafenone Hydrochloride 225 MG Extended Release Oral CapsuleAmprenavirAtrial FibrillationCisapride

Broader (7)

Adrenergic alpha-AntagonistsAlkaloidsAnti-Arrhythmia AgentsAntimalarials

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
The effect of quinidine on digoxin kinetics in cardiac patients.
The pharmacokinetics of digoxin was studied in 11 subjects before and during quinidine treatment. Renal clearances of digoxin and… 
1987
1987
Altered therapeutic range for quinidine after myocardial infarction and cardiac surgery.
Although most assays for measuring drug levels in serum determine the total concentration, effects from a drug are determined… 
1986
1986
Pigmentation induced by quinidine therapy.
Abnormalities of pigmentation are a well-known side effect of antimalarial therapy. Quinidine, an antiarrhythmic agent, is… 
Review
1983
Review
1983
The Quinidine-Digoxin Interaction in Perspective
SummaryThe administration of quinidine to patients receiving digoxin maintenance therapy results in a marked increase in the… 
Highly Cited
1980
Highly Cited
1980
Effects of quinidine on serum digoxin concentration: a prospective study.
Results of studies of 15 adults placed on quinidine therapy after their serum digoxin concentrations were stabilized showed… 
Highly Cited
1977
Highly Cited
1977
Specific determination of quinidine and (3S)-3-hydroxyquinidine in human serum by high-pressure liquid chromatography.
: A sensitive and selective HPLC assay was developed to measure quinidine and (3S)-3-hydroxyquinidine in the serum of patients… 
1976
1976
Serum quinidine concentrations: comparison of fluorescence, gas-chromatographic, and gas-chromatographic/mass-spectrometric methods.
Serum quinidine concentrations were determined in patients on chronic therapeutic doses. Although results were higher by a… 
1974
1974
Direct (non-chromatographic) quantification of drugs and their metabolites from human plasma utilizing chemical ionization mass spectrometry and stable isotope labeling: quinidine and lidocaine.
Preliminary results are reported for the quantitative determination of the antiarrhythmic agents quinidine and lidocaine in human… 
1973
1973
Examination of quinidine and quinine and their pharmaceutical preparations.
Methods for the detection and measurement of possible contaminants in quinidine and quinine and their pharmaceutical preparations… 
Highly Cited
1957
Highly Cited
1957
A possible mechanism of action of quinidine.
Quinidine increases the refractory period and depresses both the rate and amplitude of beat of isolated rabbit atria. These…