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Bioactive Metabolites from Spilanthes acmella Murr.
TLDR
These findings demonstrate for the first time the potential benefits of this medicinal plant as a rich source of high therapeutic value compounds for medicines, cosmetics, supplements and as a health food.
High therapeutic potential of Spilanthes acmella: A review
TLDR
Considering data from the literature, it could be demonstrated that S. acmella possesses diverse bioactive properties and immense utilization in medicine, health care, cosmetics and as health supplements.
New bioactive triterpenoids and antimalarial activity of Diospyros rubra Lec.
TLDR
Data is provided to support the medicinal importance of the D. rubra extracts and shows they were only shown to be active antimalarials.
Antimicrobial and Antioxidative Activities of Bioactive Constituents from Hydnophytum formicarum Jack
TLDR
The results show that the crude hexane, dichloromethane, ethyl acetate and methanol extracts exert antimicrobial and antioxidative activities and propose that Hydnophytum formicarum Jack.
8-Hydroxyquinolines: a review of their metal chelating properties and medicinal applications
TLDR
Diverse bioactivities of 8HQ and newly synthesized 8HQ-based compounds are discussed together with their mechanisms of actions and structure–activity relationships.
Vasorelaxant and Antioxidant Activities of Spilanthes acmella Murr.
TLDR
It is demonstrated that the extracts exhibit vasorelaxation via partially endothelium-induced NO and prostacyclin in a dose-dependent manner and reveal a potential source of vasodilators and antioxidants.
Sesamin and sesamol attenuate H2O2-induced oxidative stress on human neuronal cells via the SIRT1-SIRT3-FOXO3a signaling pathway
TLDR
The findings suggest that sesamin and sesamol are compounds that potentially protect neuronal cells against oxidative stress similar to that of the resveratrol, the reference compound.
Quinoline-based clioquinol and nitroxoline exhibit anticancer activity inducing FoxM1 inhibition in cholangiocarcinoma cells
TLDR
The anticancer effects of CQ and NQ against CCA cells are reported for the first time, and new insights are highlighted into the mechanism of actions of the quinoline-based compounds to disrupt FoxM1 signaling.
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