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3,4-dihydroxybenzohydroxamic acid
Known as:
Benzamide, N,3,4-trihydroxy-
, Didox
, N,3,4-trihydroxybenzamide
A ribonucleotide reductase inhibitor with activity against retroviruses. Didox inhibits retrovirus replication by depleting the deoxynucleotides…
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National Institutes of Health
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Related topics
Related topics
3 relations
Broader (3)
Antineoplastic Agents
Enzyme Inhibitors
Hydroxamic Acids
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Didox ameliorates sepsis induced acute lung injury via down regulation of IL-33 signaling pathway in mice
N. Yousif
,
Ali Najah Al-Khayyat
,
Zainab Abd Olkadhim
,
N. Hadi
,
Sara Altimimi
,
A. Altimimi
2020
Corpus ID: 214564420
Background: Sepsis very well define as life-threatening medical condition and may be characterize as dangerous condition…
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2014
2014
Abstract 5114: The chemomodulatory effects of resveratrol and didox on herceptin cytotoxicity in breast cancer cell lines
G. A. El-Latif
,
Marianne G. Tadros
,
Ashraf Naim
,
Amany Khalifa
,
A. Alabd
2014
Corpus ID: 73305582
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Herceptin is considered an essential treatment option for…
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2009
2009
The effects of combinations of a green tea extract and an active ingredient thereof, with standard antiretroviral drugs on SC-1 cells infected with the LP-BM5 virus
A. Dias
2009
Corpus ID: 68401331
The introduction of highly active antiretroviral therapy (HAART) has resulted in a significant decrease in the mortality and…
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2008
2008
Didox Treatment of MCMV Infected BALB/c Mice Results in Detrimental Outcomes
V. Go
2008
Corpus ID: 87961943
2005
2005
NFBP , a novel human protein from glial cells that interacts the NF-kappaB subunits to modulate HIV-1 LTR
J. Turchan
,
A. Chauchan
,
+9 authors
K. Khalili
2005
Corpus ID: 18628352
HIV infection continues to rise in drug abusing populations. However the combined effect of HIV and drugs of abuse have not been…
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2000
2000
Evaluation of the anti-retroviral activity and bone marrow toxicity of the novel ribonucleotide reductase inhibitors trimidox and didox and comparison with hydroxyurea in murine acquired…
May Cn
2000
Corpus ID: 78863831
1999
1999
RIBONUCLEOTIDE REDUCTASE INHIBITORS TRIMIDOX AND DIDOX ALONE OR IN COMBINATION WITH 2′,3′-DIDEOXYINOSINE (ddI) INHIBIT DEVELOPMENT OF LYMPHOMA IN MURINE AIDS
C. Mayhew
,
J. Phillips
,
N. J. Birch
,
R. Greenberg
,
H. Elford
,
V. Gallicchio
1999
Corpus ID: 74853671
1997
1997
INHIBITION OF LYMPHOMA USING RIBONUCLEOTIDE REDUCTASE INHIBITORS DIDOX OR TRIMIDOX IN THE MURINE IMMUNODEFICIENCY MAIDS MODEL: ALONE OR IN COMBINATION WITH ddI.
V. Gallicchio
,
C. Mayhew
,
O. Oliver
,
N. K. Hughes
,
J. Piper
,
H. Elford
1997
Corpus ID: 75630366
1995
1995
Beyond hydroxyurea.
T. Smart
GMHC treatment issues : the Gay Men's Health…
1995
Corpus ID: 2354726
Recent information on the compounds that inhibit cellular enzymes to suppress HIV and increase the antiviral activity of…
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1982
1982
Drug activity and therapeutic synergism in cancer treatment.
W. H. Carter
,
G. Wampler
,
D. Stablein
,
E. D. Campbell
Cancer Research
1982
Corpus ID: 190957
In work involving modeling of response surfaces to describe the effects of cancer chemotherapy treatments, it is important to…
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