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3,4-dihydroxybenzohydroxamic acid

Known as: Benzamide, N,3,4-trihydroxy-, Didox, N,3,4-trihydroxybenzamide 
A ribonucleotide reductase inhibitor with activity against retroviruses. Didox inhibits retrovirus replication by depleting the deoxynucleotides… 
National Institutes of Health

Papers overview

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2016
2016
Axonal pathology is a key contributor to long‐term disability in multiple sclerosis (MS), an inflammatory demyelinating disease… 
2016
2016
Doxorubicin (DOX) has limited efficacy in colorectal cancer due to multi-drug resistance. Resveratrol (RES) and didox (DID) are… 
2015
2015
Tamoxifen is widely used as an adjuvant therapy for patients with estrogen receptor (ERα)–positive tumors. However, the clinical… 
2013
2013
Acquired tamoxifen resistance develops in the majority of hormone-responsive breast cancers and frequently involves… 
2004
2004
Trimidox (3,4,5-trihydroxybenzamidoxime), a newly synthesized analog of didox (N,3,4-trihydroxybenzamide) reduced the activity of… 
Highly Cited
2003
Highly Cited
2003
Objective: To determine the role of oxidative stress in mediating HIV dementia and to identify novel therapeutic compounds that… 
1988
1988
A phase 1 study of a new ribonucleotide reductase inhibitor, didox, was performed by administration of escalating doses of the… 
Highly Cited
1980