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3',5'-cyclic-nucleotide phosphodiesterase activity
Known as:
3',5' cyclic-nucleotide phosphodiesterase activity
, 3': 5'-monophosphate phosphodiesterase (cyclic CMP) activity
, nucleoside-3',5-monophosphate phosphodiesterase activity
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Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate. [EC:3.1.4.17]
National Institutes of Health
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Related topics
Related topics
1 relation
phosphoric diester hydrolase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Characterization of 3',5' cyclic nucleotide phosphodiesterase activity in Y79 retinoblastoma cells: absence of functional PDE6.
J. White
,
W. Thompson
,
S. Pittler
Molecular Vision
2004
Corpus ID: 10437777
PURPOSE Previous studies identified rod photoreceptor cyclic GMP phosphodiesterase (PDE6) transcripts in the human Y79…
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Highly Cited
2003
Highly Cited
2003
Effect of sildenafil on cyclic nucleotide phosphodiesterase activity, vascular tone and calcium signaling in rat pulmonary artery
O. Pauvert
,
C. Lugnier
,
T. Keravis
,
R. Marthan
,
É. Rousseau
,
J. Savineau
British Journal of Pharmacology
2003
Corpus ID: 44914480
Sildenafil (viagra) is a potent PDE5 inhibitor and thus a relaxant drug in corpus carvernosum smooth muscle. In the present work…
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2000
2000
Effect of type‐selective inhibitors on cyclic nucleotide phosphodiesterase activity and insulin secretion in the clonal insulin secreting cell line BRIN‐BD11
M. Ahmad
,
Y. Abdel-Wahab
,
R. Tate
,
P. R. Flatt
,
N. Pyne
,
Brian L. Furman
British Journal of Pharmacology
2000
Corpus ID: 32733783
The cyclic nucleotide phosphodiesterases (PDEs) present in an insulin secreting cell line, BRIN–BD11, were characterized using…
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1992
1992
Early increase in lymphocyte cyclic nucleotide phosphodiesterase activity upon mitogenic activation of human peripheral blood mononuclear cells
N. Meskini
,
M. Hosni
,
G. Némoz
,
M. Lagarde
,
A. Prigent
Journal of Cellular Physiology
1992
Corpus ID: 22096266
Cyclic nucleotide phosphodiesterase activity of human peripheral blood mononuclear cells was significantly increased following a…
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1985
1985
Correlation between inhibition of a cyclic GMP phosphodiesterase and relaxation of canine tracheal smooth muscle.
J. Polson
,
J. Krzanowski
,
A. Szentivanyi
Biochemical Pharmacology
1985
Corpus ID: 1307280
1977
1977
Studies on the synergistic effect of androgen on the stimulation of progestin secretion by FSH in cultured rat granulosa cells: A search for the mechanism of action
A. Nimrod
Molecular and Cellular Endocrinology
1977
Corpus ID: 23918974
Review
1976
Review
1976
In vitro inhibition of cyclic AMP phosphodiesterase by cortisol
J. Schmidtke
,
T. Wienker
,
M. Flügel
,
W. Engel
Nature
1976
Corpus ID: 4239849
HORMONAL effects on cyclic nucleotide phosphodiesterase activity are assumed to play an important role in the regulation of…
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1976
1976
Diurnal rhythm in rat pineal cyclic nucleotide phosphodiesterase activity
K. Minneman
,
L. Iversen
Nature
1976
Corpus ID: 4155135
MANY substances in the rat pineal organ exhibit marked diurnal variations; some of these fluctuations are circadian, that is…
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Highly Cited
1973
Highly Cited
1973
Development of cyclic AMP metabolism in rat liver. A correlative study of tissue levels of cyclic AMP, accumulation of cyclic AMP in slices, adenylate cyclase activity and cyclic nucleotide…
Thoralf Christoffersen
,
Jørg Mørland
,
J. Osnes
,
Ivar Øye
Biochimica et Biophysica Acta
1973
Corpus ID: 32293901
1973
1973
Inhibition of cortical neurones by imidazole and some derivatives.
J. Godfraind
,
K. Krnjević
,
H. Maretić
,
R. Pumain
Canadian Journal of Physiology and Pharmacology
1973
Corpus ID: 45514851
Systematic tests of imidazole and 15 derivatives, applied by microiontophoresis in anesthetized cats, showed a high inhibitory…
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