3',5'-cyclic-nucleotide phosphodiesterase activity

Known as: 3',5' cyclic-nucleotide phosphodiesterase activity, 3': 5'-monophosphate phosphodiesterase (cyclic CMP) activity, nucleoside-3',5-monophosphate phosphodiesterase activity 
Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate. [EC:3.1.4.17]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1969-2018
051019692018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
The trace element zinc affects several aspects of immune function, such as the release of proinflammatory cytokines from… (More)
  • figure 1
  • table I
  • figure 2
  • figure 3
  • figure 5
Is this relevant?
2005
2005
Previous reports have described both increased and decreased cyclic nucleotide phosphodiesterase (PDE) activity in dystrophic… (More)
Is this relevant?
2004
2004
PURPOSE Previous studies identified rod photoreceptor cyclic GMP phosphodiesterase (PDE6) transcripts in the human Y79… (More)
Is this relevant?
Highly Cited
2004
Highly Cited
2004
We identify a new enzymatic activity underlying metastasis in breast cancer and describe its susceptibility to therapeutic… (More)
Is this relevant?
2003
2003
(1) Sildenafil (viagra) is a potent PDE5 inhibitor and thus a relaxant drug in corpus carvernosum smooth muscle. In the present… (More)
Is this relevant?
2000
2000
1. The cyclic nucleotide phosphodiesterases (PDEs) present in an insulin secreting cell line, BRIN - BD11, were characterized… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
Recent reports have shown that phosphodiesterase (PDE) inhibitors suppress production of tumour necrosis factor-alpha (TNF-alpha… (More)
Is this relevant?
1991
1991
The effect of regucalcin, a calcium-binding protein isolated from rat liver cytosol, on Ca2+/calmodulin-dependent cyclic… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
1980
1980
The effects of phorbol ester application and of other mitogenic treatments on the activity of 3',5'-cyclic-nucleotide… (More)
Is this relevant?
1971
1971
The distribution of cyclic 3',5'-nucleotide phosphodiesterase activity in rat cerebral cortex was determined by cytochemical… (More)
Is this relevant?