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3',5'-cyclic-nucleotide phosphodiesterase activity

Known as: 3',5' cyclic-nucleotide phosphodiesterase activity, 3': 5'-monophosphate phosphodiesterase (cyclic CMP) activity, nucleoside-3',5-monophosphate phosphodiesterase activity 
Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate. [EC:3.1.4.17]
National Institutes of Health

Papers overview

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2017
2017
Photoactivated adenylyl cyclase (PAC) and guanylyl cyclase rhodopsin increase the concentrations of intracellular cyclic… Expand
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Highly Cited
2005
Highly Cited
2005
The trace element zinc affects several aspects of immune function, such as the release of proinflammatory cytokines from… Expand
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2003
2003
(1) Sildenafil (viagra) is a potent PDE5 inhibitor and thus a relaxant drug in corpus carvernosum smooth muscle. In the present… Expand
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Highly Cited
2003
Highly Cited
2003
Absorbance measurements at 660 nm of calmodulin (CaM) dependent cyclic nucleotide phosphodiesterase activity under cell free… Expand
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2000
2000
1. The cyclic nucleotide phosphodiesterases (PDEs) present in an insulin secreting cell line, BRIN - BD11, were characterized… Expand
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1995
1995
Bryostatin 1, a novel antineoplastic agent and protein kinase C (PKC) activator, has been found to induce myalgia (muscle pain… Expand
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1991
1991
The effect of regucalcin, a calcium-binding protein isolated from rat liver cytosol, on Ca2+/calmodulin-dependent cyclic… Expand
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1990
1990
Experiments were carried out in order to isolate and characterize the cyclic nucleotide phosphodiesterase activities in primary… Expand
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Highly Cited
1987
Highly Cited
1987
Four cyclic nucleotide phosphodiesterase (PDE) activities were separated from low-speed supernatants of homogenates of human… Expand
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1981
1981
Addition of cholera toxin (100 ng/ml) to quiescent cultures of Swiss 3T3 cells acts synergistically with serum (2-4%), insulin… Expand
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