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2-acetylaminofluorene N-deacetylase

Known as: 2-acetylaminofluorene amidohydrolase, AAF N-deacetylase, AAF-arylacetamide deacetylase 
National Institutes of Health

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Amidohydrolases

Papers overview

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2013
2013
Nuclear magnetic resonance at the picomole level of a DNA adduct.
We investigate the limit of detection for obtaining NMR data of a DNA adduct using modern microscale NMR instrumentation, once… 
1998
1998
Interfacing of CE in a PVP matrix to ion trap mass spectrometry: analysis of isomeric and structurally related (N-acetylamino)fluorene-modified oligonucleotides.
This work demonstrates the interfacing of capillary electrophoresis in a poly(N-vinylpyrrolidone) (PVP) solution to electrospray… 
1995
1995
Modulation of DNA adduct formation by successive exposures of DNA to small and bulky chemical carcinogens.
The effect of a carcinogen-DNA adduct on the formation of a second adduct upon subsequent exposure to a second carcinogen was… 
1994
1994
Central administration of the endopeptidase 24.15 inhibitor cFP-AAF-pAB suggests dynorphin as the endogenous ligand underlying behavioral effects of milk in the fetal rat
1988
1988
Targeted mutations induced by a single acetylaminofluorene DNA adduct in mammalian cells and bacteria.
Mutagenic specificity of 2-acetylaminofluorene (AAF) has been established in mammalian cells and several strains of bacteria by… 
1985
1985
Purification and chemical properties of anti-complementary polysaccharide from the leaves of Artemisia princeps.
The polysaccharide fraction from the leaves of ARTEMISIA PRINCEPS Pamp (Japanese name = Gaiyō) showed a potent anti-complementary… 
1985
1985
Analysis of metabolites of 2-acetylaminofluorene generated in an embryo culture system. Relationship of biotransformation to teratogenicity in vitro.
1984
1984
Metabolism and DNA adduct formation of 2-acetylaminofluorene by bladder explants from human, dog, monkey, hamster and rat.
Cultured bladder explants from human, dog, monkey, hamster and rat were used to study the metabolism, and DNA-adduct formation of… 
Highly Cited
1963
Highly Cited
1963
The N- and ring-hydroxylation of 2-acetylaminofluorene and the failure to detect N-acetylation of 2-aminofluorene in the dog.
N -Hydroxy-2-acetylaminofluorene ( N -hydroxy-AAF), in conjugated form, was identified as a urinary metabolite of 2… 
Highly Cited
1960
Highly Cited
1960
The N- and ringhydroxylation of 2-acetylaminofluorene during carcinogenesis in the rat.
The new major metabolite of 2-acetylaminofluorene (AAF) in the rat, N -hydroxy-AAF, was excreted in the urine as a conjugate in… 
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