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2',5'-oligoadenylate

Known as: 2'-5'-Oligoadenylate, oligos, 2'-5' Oligoadenylate 
An oligonucleotide synthesized from adenosine triphosphate (ATP) by enzymes in the 2'-5'-oligoadenylate synthase family. The production of 2'-5… 
National Institutes of Health

Related topics

Related topics

7 relations

Narrower (1)

2'-5'-oligoadenylate trimer

Broader (5)

Adenine NucleotidesAntiviral AgentsOligoribonucleotidesProtein Synthesis Inhibitors
Oligonucleotides

Papers overview

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Highly Cited
2011
Highly Cited
2011
Nucleoside modifications in RNA limit activation of 2′-5′-oligoadenylate synthetase and increase resistance to cleavage by RNase L
The interferon-induced enzymes 2′-5′-oligoadenylate synthetase (OAS) and RNase L are key components of innate immunity involved… 
Highly Cited
2005
Highly Cited
2005
Phosphodiesterase-5 Inhibition With Sildenafil Attenuates Cardiomyocyte Apoptosis and Left Ventricular Dysfunction in a Chronic Model of Doxorubicin Cardiotoxicity
Background—Sildenafil, a phosphodiesterase-5 inhibitor, induces cardioprotection against ischemia/reperfusion injury via opening… 
Highly Cited
2002
Highly Cited
2002
New Polylactide/Layered Silicate Nanocomposites. 1. Preparation, Characterization, and Properties
New polylactide (PLA)/layered silicate nanocomposites have been prepared successfully by simple melt extrusion of PLA and… 
Highly Cited
2002
Highly Cited
2002
Genome Sequence and Analysis of the Oral Bacterium Fusobacterium nucleatum Strain ATCC 25586
ABSTRACT We present a complete DNA sequence and metabolic analysis of the dominant oral bacterium Fusobacterium nucleatum… 
Highly Cited
2001
Highly Cited
2001
Inhibition of zebrafish fgf8 pre‐mRNA splicing with morpholino oligos: A quantifiable method for gene knockdown
Antisense morpholino oligonucleotides (MO) have been used successfully in zebrafish and Xenopus to knock down gene function by… 
Highly Cited
1992
Highly Cited
1992
Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate.
Highly Cited
1991
Highly Cited
1991
Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein
Highly Cited
1989
Highly Cited
1989
Location of high affinity Ca2 +-binding sites within the predicted transmembrahe domain of the sarco-plasmic reticulum Ca2+-ATPase
CATION pumps bind and translocate ions with the intermediate formation of a phosphoenzyme. In spite of extensive knowledge of the… 
Highly Cited
1973
Highly Cited
1973
The Structure of Plant Cell Walls: I. The Macromolecular Components of the Walls of Suspension-cultured Sycamore Cells with a Detailed Analysis of the Pectic Polysaccharides.
This is the first in a series of papers dealing with the structure of cell walls isolated from suspension-cultured sycamore cells… 
Highly Cited
1966
Highly Cited
1966
Adenylate oligomers in single- and double-strand conformation.
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